Acriflavine Hydrochloride (CAS 8063-24-9) is more than just an antiseptic; it's a fascinating chemical entity with a rich history and complex properties that underpin its diverse applications. Understanding its chemistry is key for any B2B professional looking to leverage its benefits. NINGBO INNO PHARMCHEM CO.,LTD., as a knowledgeable manufacturer and supplier, provides insights into this essential compound.

Understanding the Chemical Identity of Acriflavine Hydrochloride

Acriflavine Hydrochloride is not a single compound but rather a mixture of acridine derivatives, primarily 3,6-diamino-10-methylacridinium chloride and 3,6-diaminoacridine. This composition, developed by Paul Ehrlich in 1912, gives it unique staining and antimicrobial properties. Its hydrochloride salt form enhances its solubility and utility in various aqueous applications.

Key Chemical Properties:

  • Appearance: Typically a brownish-orange to yellow crystalline powder.
  • Solubility: Freely soluble in water, forming a colored solution, and soluble in methanol and DMSO.
  • Molecular Formula: The mixture's general representation can be complex, but key components are C14H14N3Cl (for the methylated derivative) and C13H11N3 (for proflavine).
  • Mechanism of Action: Its antimicrobial and staining effects are largely attributed to its ability to intercalate into DNA, disrupting cellular processes and vital functions of microorganisms. It also exhibits antiviral properties, notably as a protease inhibitor.
  • Fluorescence: It exhibits fluorescence, making it useful as a biological stain and contrast agent in microscopy.

Synthesis and Manufacturing Considerations

The synthesis of Acriflavine Hydrochloride involves complex organic chemistry pathways, typically starting from aniline derivatives and undergoing cyclization and further modifications. As a manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. focuses on ensuring precise control over these synthesis steps to achieve the desired purity and composition. Key aspects for manufacturers include:

  • Purity and Isomer Control: Maintaining the correct ratio of acriflavine and proflavine components, along with minimizing impurities, is critical for consistent product performance.
  • Quality Assurance: Rigorous testing using methods like HPLC is essential to confirm purity, identity, and adherence to specifications.
  • Handling and Safety: Acriflavine Hydrochloride is classified as a hazardous substance, requiring careful handling and appropriate safety measures during production and transportation.

Why Partner with NINGBO INNO PHARMCHEM CO.,LTD. for Your Chemical Needs?

For professionals in the pharmaceutical, veterinary, and research sectors, sourcing high-quality chemical intermediates is crucial. NINGBO INNO PHARMCHEM CO.,LTD. offers expertise in the manufacturing and supply of Acriflavine Hydrochloride. Our commitment to chemical integrity, reliable production, and competitive pricing ensures that when you buy Acriflavine HCl from us, you receive a product that meets the highest standards. Understanding the chemistry empowers us to deliver superior products and support. Contact us to learn more about our Acriflavine Hydrochloride and how our manufacturing expertise can benefit your business.