Niclosamide, identified by its CAS number 50-65-7, is a compound with a rich history of application in pest control and animal health. Beyond its established uses as a molluscicide and anthelmintic, recent scientific research has uncovered promising new therapeutic potentials, positioning it as a molecule of significant interest in drug discovery. As a dedicated supplier of this versatile chemical, we are keen to share insights into its scientific underpinnings.

The primary and most recognized application of Niclosamide is its efficacy as a molluscicide and anthelmintic. Its action against snails and tapeworms stems from its ability to disrupt cellular energy production. Specifically, Niclosamide uncouples oxidative phosphorylation in the mitochondria of target organisms. This process inhibits ATP synthesis, leading to energy depletion and ultimately cell death. In tapeworms, this effect is potent, dismantling the scolex and segments upon contact. This mechanism of action makes it a critical ingredient for veterinary pharmaceuticals and agricultural pest management products.

Beyond its traditional roles, Niclosamide has garnered attention for its potential therapeutic applications in human health. Research has indicated that Niclosamide can act as an inhibitor of various signaling pathways crucial in disease progression, particularly in cancer and viral infections. For instance, it has been identified as a STAT3 inhibitor, a key target in many cancer therapies. Studies have also demonstrated its antiviral properties, including inhibitory effects against SARS-CoV. These emerging applications highlight Niclosamide's broad biological activity and its potential as a lead compound for drug development.

For researchers and pharmaceutical companies exploring these new avenues, sourcing high-purity Niclosamide is paramount. Consistency in chemical properties, such as its yellowish crystalline appearance and assay exceeding 98%, ensures that experimental results are reliable and reproducible. As a manufacturer, we ensure our Niclosamide product meets these stringent requirements, providing researchers with the quality material they need for their studies. We offer various quantities, allowing for seamless transition from lab-scale research to pilot studies.

The scientific community continues to explore Niclosamide's multifaceted capabilities. Its established safety profile in certain veterinary applications, coupled with its diverse biological targets, makes it an attractive candidate for further investigation. Whether for developing new crop protection agents or exploring novel therapeutic interventions, understanding the science behind Niclosamide is key.

In conclusion, Niclosamide is a remarkable chemical with proven efficacy in pest control and a growing profile in therapeutic research. Its ability to disrupt cellular energy pathways underlies its effectiveness. By providing high-quality Niclosamide, we support the ongoing scientific endeavors that aim to harness its full potential, from safeguarding crops to developing future medicines.