Polyvinylpyrrolidone (PVP) is a widely used polymer in the pharmaceutical industry, available in various grades characterized by their K-value, which correlates with molecular weight and viscosity. Among the most common are PVP K15 and PVP K30. Understanding the nuances between these grades is critical for successful drug formulation. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality pharmaceutical-grade PVP to meet diverse manufacturing requirements.

PVP K15, typically with a molecular weight around 9,700 g/mol, offers excellent binding properties with relatively low viscosity. This makes it an ideal choice for applications requiring good tablet hardness and friability at lower concentrations, particularly in direct compression or dry granulation processes where a less viscous binder is preferred. The applications of PVP K15 are diverse, ranging from tablet binding to its use in specialized pharmaceutical preparations where a lighter touch is needed.

PVP K30, with a higher molecular weight of approximately 40,000 g/mol, exhibits stronger binding capabilities and higher viscosity. This grade is highly effective in wet granulation processes, forming robust granules and producing tablets with excellent mechanical strength. Moreover, PVP K30 is particularly noted for its ability to enhance the solubility of poorly soluble drugs, acting as a matrix former in solid dispersion systems. Exploring the PVP K30 benefits for solubility enhancement is a key area of pharmaceutical research.

When considering pharmaceutical grade polyvinylpyrrolidone K15 versus pharmaceutical grade polyvinylpyrrolidone K30, formulators must evaluate their specific needs. For primary tablet binding, K15 offers efficiency with lower viscosity, while K30 provides superior binding strength and is more effective for solubility enhancement and higher granulation viscosity requirements.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the pharmaceutical sector with premium-grade PVP. Our commitment to quality in polyvinylpyrrolidone manufacturing ensures that you receive consistent and reliable products. Whether you require the specific binding characteristics of K15 or the solubility-enhancing power of K30, we offer the expertise and products to facilitate your formulation success. Consult with us to determine the optimal PVP grade for your project.