In the intricate world of advanced organic synthesis, the availability of versatile and high-purity building blocks is paramount. Researchers constantly seek compounds that offer unique reactivity and structural possibilities to construct complex molecules. Among these valuable reagents, 1,10-Phenanthroline-5,6-Dione, identified by its CAS number 27318-90-7, stands out as a significant heterocyclic intermediate.

This compound, typically appearing as a yellow solid, is characterized by its molecular formula C12H6N2O2 and a molecular weight of approximately 210.19 g/mol. Its quinone derivative structure, stemming from the 1,10-phenanthroline scaffold, endows it with distinct chemical properties that make it highly sought after in synthetic organic chemistry. The high purity, often ≥98%, offered by reputable manufacturers ensures that reactions proceed as expected, minimizing by-product formation and maximizing yields.

Applications in Novel Molecule Synthesis

The utility of 1,10-Phenanthroline-5,6-Dione extends across various domains of organic synthesis. Its dicarbonyl functionality, adjacent to the nitrogen-containing heterocyclic rings, provides multiple avenues for chemical transformations. These include:

  • Condensation Reactions: It readily undergoes condensation reactions with diamines to form quinoxaline derivatives. This is a fundamental pathway for synthesizing a range of heterocyclic systems, often found in pharmaceuticals and advanced materials.
  • Metal Complexation: The presence of nitrogen atoms in the phenanthroline core makes it an excellent ligand for coordinating with metal ions. This property is exploited in the synthesis of metallodrugs and catalysts, where the specific coordination chemistry can influence reactivity and biological activity. Studies have shown its utility in creating complexes with promising anthelmintic properties.
  • Functionalization and Derivatization: The reactive sites on the molecule allow for further functionalization, enabling the creation of diverse libraries of compounds. This is invaluable for drug discovery programs seeking to explore structure-activity relationships (SAR).

Sourcing High-Quality 1,10-Phenanthroline-5,6-Dione

For scientists engaged in complex synthetic projects, the ability to purchase 1,10-Phenanthroline-5,6-Dione from a reliable manufacturer is essential. When considering where to buy this chemical, prioritizing suppliers who provide detailed specifications, such as CAS number, molecular formula, molecular weight, and purity, is crucial. Looking for manufacturers who explicitly state their assay and offer comprehensive technical data will save significant time and resources in R&D. For instance, a supplier might offer it as a yellow solid powder, indicating its physical form.

The price of such specialized intermediates can vary, but a consistent supplier in China often provides competitive pricing, especially for bulk orders. Researchers can inquire about pricing and bulk purchase options to ensure cost-effectiveness for their synthesis projects. Furthermore, understanding the storage recommendations, typically in a cool, dry environment, ensures that the compound retains its integrity from the supplier to the laboratory.

In essence, 1,10-Phenanthroline-5,6-Dione serves as a powerful and adaptable building block for synthetic chemists. Its well-defined properties and reactive potential make it an indispensable tool in the creation of novel organic molecules. By securing high-purity material from trusted manufacturers, researchers can confidently explore its synthetic capabilities and drive innovation in various scientific fields.