In the intricate landscape of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. 1,3-Adamantanediol monoacrylate, identified by CAS number 216581-76-9, serves as a vital building block in the synthesis of various complex organic molecules, including potential drug candidates. For R&D scientists and procurement specialists, understanding this compound and securing a dependable supplier is essential for project success.

The Role of Adamantane Derivatives in Pharmaceuticals

Adamantane and its derivatives have garnered significant attention in medicinal chemistry. The rigid, lipophilic, and cage-like structure of adamantane can influence a drug molecule's pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion (ADME). Incorporating adamantane moieties can:

  • Enhance Lipophilicity: Improving membrane permeability and oral bioavailability.
  • Increase Metabolic Stability: Protecting susceptible parts of a molecule from enzymatic degradation, leading to longer drug half-lives.
  • Improve Receptor Binding: The specific three-dimensional structure can facilitate better interactions with target proteins or enzymes.

1,3-Adamantanediol monoacrylate, with its reactive acrylate group, offers a convenient handle for further chemical modifications, allowing medicinal chemists to precisely introduce the adamantane framework into larger, more complex structures.

Specifications for Pharmaceutical Grade Intermediates

When sourcing 1,3-Adamantanediol monoacrylate for pharmaceutical applications, stringent quality control is non-negotiable. Key considerations for buyers include:

  • High Purity: Typically, a purity of 99% or higher is required to minimize side reactions and ensure the final API meets regulatory standards.
  • Detailed Specification Sheets: Manufacturers should provide comprehensive data, including purity by GC, molecular structure confirmation, and absence of critical impurities.
  • Traceability: Ensuring batch-to-batch consistency and traceability is crucial for pharmaceutical development and manufacturing.
  • Secure Supply Chain: A reliable manufacturer and supplier are vital to maintain the continuity of drug development and production timelines.

Why Buy from a Trusted Manufacturer?

Purchasing pharmaceutical intermediates like 1,3-Adamantanediol monoacrylate requires a high degree of trust in the supplier. A reputable chemical manufacturer will not only guarantee the product's specifications but also adhere to stringent quality management systems. They can offer technical support and work collaboratively with clients to meet specific project needs. For those looking to buy this crucial intermediate, engaging with experienced suppliers in China and beyond provides access to quality products at competitive prices. Ensuring a stable supply of high-purity 1,3-Adamantanediol monoacrylate is a strategic step for any pharmaceutical company aiming for successful drug discovery and development.