1,3-Dimethylbarbituric acid (CAS: 769-42-6) is a compound of significant interest in the chemical and pharmaceutical industries, primarily recognized for its role as a key intermediate in the synthesis of Oseltamivir. However, its utility extends beyond this single application, offering versatility for various chemical synthesis processes. Understanding its properties and broader applications is crucial for researchers and procurement specialists seeking high-quality chemical raw materials. NINGBO INNO PHARMCHEM CO.,LTD. offers insights into this important chemical.

Understanding the Properties of 1,3-Dimethylbarbituric Acid

As a well-characterized chemical entity, 1,3-Dimethylbarbituric acid presents a set of physical and chemical properties that make it valuable for synthesis:

  • Appearance: Typically supplied as a White to cream crystalline powder, facilitating easy handling and measurement in laboratory and industrial settings.
  • Purity: Available with a high assay, often exceeding 99.0% via HPLC, ensuring minimal impurities and consistent reactivity.
  • Melting Point: Its defined melting point, generally between 121-123 °C (lit.), is a key indicator of purity and aids in process control.
  • Solubility: It is soluble in methanol, forming a clear solution, which is beneficial for reaction setup and analysis. It is also reported as soluble in hot water.
  • Molecular Structure: With the molecular formula C6H8N2O3, it is a derivative of barbituric acid, featuring methyl groups at the 1 and 3 nitrogen positions.

These properties collectively make 1,3-Dimethylbarbituric acid an attractive candidate for various synthetic routes, especially when high purity and predictable behavior are required. When seeking to buy this compound, looking for these specifications from a reputable supplier is essential.

Diverse Applications in Chemical Synthesis

While its role as an Oseltamivir intermediate is its most prominent application, 1,3-Dimethylbarbituric acid is also a valuable tool in broader chemical synthesis:

  • Pharmaceutical Intermediates: Beyond Oseltamivir, it can serve as a building block for synthesizing other pharmaceutical compounds and complex heterocyclic structures, contributing to drug discovery and development.
  • Organic Synthesis Reagent: It participates in various organic reactions, including Knoevenagel condensations with aromatic aldehydes, which are useful for creating carbon-carbon double bonds and synthesizing a wide array of organic molecules. Researchers often look for this compound to enable specific synthetic transformations.
  • Research and Development: Its reactivity makes it a subject of study in academic and industrial research for developing novel synthetic methodologies and exploring new chemical entities with potential applications.

For businesses looking to procure 1,3-Dimethylbarbituric acid for their synthesis needs, understanding these applications helps in identifying reliable manufacturers and understanding its market value. We encourage you to contact NINGBO INNO PHARMCHEM CO.,LTD. for competitive quotes and detailed product information to facilitate your next synthesis project. As a leading supplier in China, we are committed to providing high-quality materials to support your chemical endeavors.