In the highly regulated and precision-driven pharmaceutical industry, the selection of intermediates is a critical step in drug synthesis. Procurement managers and R&D scientists are constantly seeking compounds that offer high purity, consistent quality, and reliable availability. 1,4-Dichlorobutane (CAS: 110-56-5) fits this profile perfectly, serving as a vital intermediate in the creation of numerous active pharmaceutical ingredients (APIs).

The Chemical Profile of 1,4-Dichlorobutane for Pharmaceutical Use

1,4-Dichlorobutane is characterized by its colorless, transparent liquid appearance and a high assay of ≥99.0%. Its molecular formula, C4H8Cl2, and CAS number 110-56-5 are standard identifiers for this essential chemical. For pharmaceutical applications, where even minute impurities can have significant consequences, sourcing this compound from manufacturers who guarantee stringent quality control is non-negotiable. Its physical properties, such as a boiling point of 161-163°C, are well-documented and considered when designing synthetic routes. When you need to purchase this, looking for specifications like low moisture content (≤0.2%) is a good practice.

Role in API Synthesis and Drug Development

The bifunctional nature of 1,4-Dichlorobutane makes it an exceptionally useful synthon in organic chemistry, particularly for building complex molecular structures common in APIs. It can participate in various reactions, including nucleophilic substitutions, leading to the formation of cyclic compounds or the extension of carbon chains. Pharmaceutical researchers often utilize it to introduce specific functionalities or to create the backbone of drug molecules. For procurement teams, identifying a dependable supplier for this intermediate ensures that drug development pipelines remain uninterrupted.

Procurement Advantages from China-Based Manufacturers

For global pharmaceutical companies and contract manufacturing organizations, sourcing intermediates like 1,4-Dichlorobutane from China offers significant strategic advantages. China-based manufacturers often possess large-scale production capacities, allowing for cost-effective bulk supply. Furthermore, many are committed to meeting international quality standards, making them competitive partners for the pharmaceutical sector. When you are looking to buy this critical intermediate, partnering with a manufacturer that provides comprehensive documentation, such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), is essential.

Your Partner for High-Quality Pharmaceutical Intermediates

We understand the stringent demands of the pharmaceutical industry. Our commitment is to supply 1,4-Dichlorobutane that meets the highest purity requirements, backed by robust quality control and a stable supply chain. We encourage research scientists and procurement managers to request a quote for 1,4-Dichlorobutane and to inquire about our custom synthesis capabilities. By choosing us as your supplier, you gain access to a reliable source of a key pharmaceutical building block, enabling you to advance your drug development and manufacturing processes with confidence.