In the intricate world of organic synthesis and pharmaceutical development, the availability of high-quality, reliable chemical intermediates is non-negotiable. Among these essential compounds is 1-Acetylpiperazine, identified by CAS number 13889-98-0. This molecule serves as a crucial building block, enabling the creation of more complex structures and ultimately contributing to the development of new therapeutic agents and advanced materials. Understanding its properties, applications, and how to source it effectively is key for R&D scientists and procurement specialists.

The Chemical Profile of 1-Acetylpiperazine

1-Acetylpiperazine (C6H12N2O) is characterized by a molecular weight of 128.17. Its physical properties, such as a melting point typically ranging from 31-34 °C, indicate it can exist as a solid or a molten liquid depending on ambient conditions. The compound is noted for its pale yellow crystalline appearance. A purity of 97% minimum is commonly sought after by users in demanding applications, ensuring predictable reactivity and minimal side reactions in synthesis pathways. Its boiling point, around 257.9 ± 33.0 °C at atmospheric pressure, suggests thermal stability suitable for many standard chemical processes.

Versatility in Organic Synthesis

The utility of 1-Acetylpiperazine spans various fields within chemical research and industry. Primarily, it functions as a vital pharmaceutical intermediate. Its structure lends itself to being incorporated into drug molecules, acting as a core scaffold or a functional group that imparts specific biological activity. Beyond pharmaceuticals, it is a valuable reagent in general organic synthesis, allowing chemists to construct diverse molecular architectures. Researchers looking to buy 1-Acetylpiperazine often seek it for its role in creating heterocyclic compounds or modifying existing molecular structures.

Sourcing Strategies for Procurement Managers

For professionals tasked with sourcing chemicals like 1-Acetylpiperazine, identifying reliable suppliers and manufacturers is a priority. China is a significant source for these materials, offering competitive pricing and a wide selection of producers. When you decide to purchase 1-Acetylpiperazine, it is advisable to look for suppliers who can guarantee:

  • Consistent Purity: Ensuring batches meet or exceed the 97% minimum purity requirement.
  • Reliable Supply Chain: Stable production and timely delivery to support your project timelines.
  • Comprehensive Documentation: Availability of Certificates of Analysis (CoA) and other necessary quality documentation.
  • Responsive Customer Support: Efficient communication for inquiries and order processing.

Engaging directly with a manufacturer can often yield better terms and more direct control over product quality.

Driving Innovation with Quality Intermediates

The selection of chemical intermediates directly impacts the success of research and development efforts. By choosing to order 1-Acetylpiperazine from reputable sources, scientists can confidently proceed with their experimental designs, knowing they are working with a well-characterized and high-purity material. This focus on quality not only enhances experimental reproducibility but also accelerates the journey from laboratory discovery to market-ready products.

In summary, 1-Acetylpiperazine (CAS 13889-98-0) is an indispensable intermediate for advanced chemical synthesis. Understanding its properties and strategic sourcing from reliable Chinese manufacturers ensures that researchers and industries have access to the quality materials needed to drive innovation forward.