Why 1-Bromo-2,3,4-trifluorobenzene is Crucial for Modern Synthesis
The advancement of organic chemistry, particularly in the fields of pharmaceuticals and agrochemicals, relies heavily on the availability of specialized building blocks. 1-Bromo-2,3,4-trifluorobenzene (CAS 176317-02-5) stands out as a highly versatile intermediate, prized for its unique structural features and reactivity. Its incorporation into synthesis pathways can impart desirable properties to the final molecules, making it an essential component for many research and industrial applications.
The presence of three fluorine atoms on the benzene ring significantly influences the electron distribution and reactivity of 1-Bromo-2,3,4-trifluorobenzene. This electronic effect, combined with the bromine atom, makes it an excellent substrate for a variety of coupling reactions, nucleophilic substitutions, and Grignard reagent formation. For chemical manufacturers and procurement specialists, understanding these characteristics is key to effectively utilizing this compound.
In the pharmaceutical industry, the introduction of fluorine atoms into drug molecules can enhance lipophilicity, improve metabolic stability, and modulate binding affinity to target receptors. Consequently, 1-Bromo-2,3,4-trifluorobenzene is sought after as a precursor for a range of active pharmaceutical ingredients (APIs). Similarly, in agrochemical research, fluorinated compounds often exhibit increased biological activity and environmental persistence, leading to more effective crop protection agents. Businesses looking to buy this intermediate can benefit from the expertise of China-based manufacturers who specialize in producing high-purity fluorinated chemicals.
When sourcing 1-Bromo-2,3,4-trifluorobenzene, it is crucial to partner with a reliable supplier that can provide consistent quality and volume. Manufacturers offering this compound typically highlight its 99% purity and provide detailed specifications such as density (around 1.777) and refractive index (around 1.4870). These parameters are critical for ensuring successful scale-up and reproducible results in laboratory and production settings.
For companies seeking to innovate in drug discovery or agrochemical development, acquiring high-quality 1-Bromo-2,3,4-trifluorobenzene is a foundational step. By connecting with leading manufacturers and suppliers, businesses can secure the materials needed to drive their research and development forward, benefiting from the competitive landscape and manufacturing prowess available in regions like China.
Perspectives & Insights
Bio Analyst 88
“1-Bromo-2,3,4-trifluorobenzene (CAS 176317-02-5) stands out as a highly versatile intermediate, prized for its unique structural features and reactivity.”
Nano Seeker Pro
“Its incorporation into synthesis pathways can impart desirable properties to the final molecules, making it an essential component for many research and industrial applications.”
Data Reader 7
“The presence of three fluorine atoms on the benzene ring significantly influences the electron distribution and reactivity of 1-Bromo-2,3,4-trifluorobenzene.”