In the relentless pursuit of novel therapeutics, the quality and availability of chemical intermediates are paramount. For research scientists and product developers in the pharmaceutical sector, understanding the utility of compounds like 1-Bromo-2-fluoro-4-nitrobenzene (CAS: 185331-69-5) is crucial. This article delves into why this specific molecule is a cornerstone in modern drug discovery and how to best secure its supply.

The Molecular Foundation of Drug Synthesis

1-Bromo-2-fluoro-4-nitrobenzene, a halogenated aromatic compound with the chemical formula C6H3BrFNO2, is highly valued for its precise reactivity. Its structure, featuring a bromine atom, a fluorine atom, and a nitro group on a benzene ring, allows for targeted chemical modifications. This makes it an ideal starting material or intermediate for constructing complex molecular architectures that form the basis of many active pharmaceutical ingredients (APIs). Researchers often leverage its ability to undergo nucleophilic aromatic substitution and other selective reactions to introduce specific functional groups.

Driving Pharmaceutical Advancements

The applications of 1-Bromo-2-fluoro-4-nitrobenzene in the pharmaceutical industry are diverse and impactful:

  • Drug Discovery: It serves as a key building block in the synthesis of new chemical entities (NCEs) being investigated for various therapeutic areas, including oncology, infectious diseases, and inflammatory conditions. Its unique structural features can impart desirable pharmacokinetic properties to the final drug molecule.
  • Process Development: For established APIs, sourcing high-purity 1-Bromo-2-fluoro-4-nitrobenzene from a reliable manufacturer ensures consistent batch-to-batch quality, which is critical for regulatory compliance and manufacturing efficiency.
  • Intermediate Synthesis: It is frequently used to create more complex intermediates, streamlining multi-step synthesis routes for challenging drug targets.

Procuring High-Quality 1-Bromo-2-fluoro-4-nitrobenzene

When your research or production demands high-purity 1-Bromo-2-fluoro-4-nitrobenzene, sourcing from a reputable 1-Bromo-2-fluoro-4-nitrobenzene supplier in China is often the most cost-effective approach. As a leading 1-Bromo-2-fluoro-4-nitrobenzene manufacturer, we prioritize exceptional quality, with assays typically exceeding 98.0%. It is vital to seek suppliers who can provide comprehensive documentation, including Certificates of Analysis (CoA), to verify purity and specifications. Understanding the 1-Bromo-2-fluoro-4-nitrobenzene price is crucial for budgeting, and we encourage inquiries for bulk orders to secure advantageous pricing. Remember to always confirm the CAS number (185331-69-5) to ensure you are acquiring the correct compound.

Building a Robust Supply Chain

A strong partnership with a chemical supplier is foundational to successful pharmaceutical development. A good 1-Bromo-2-fluoro-4-nitrobenzene manufacturer offers not just the product but also technical support and reliable logistics. Proper storage, such as keeping the material in a cool, dry, and well-ventilated place, away from light, is essential for maintaining its chemical integrity. By choosing wisely, you ensure that this critical intermediate contributes effectively to your pharmaceutical innovation pipeline.

This information serves as a guide for pharmaceutical professionals aiming to source and utilize 1-Bromo-2-fluoro-4-nitrobenzene efficiently and effectively.