In the realm of organic synthesis, certain chemical intermediates serve as foundational elements for creating more complex molecules. 1-Bromo-3,5-dimethoxybenzene (CAS: 20469-65-2) is one such compound, recognized for its utility in various synthetic pathways, particularly within the pharmaceutical and fine chemical industries. Researchers and procurement specialists often seek this compound for its specific chemical properties and reactivity.

The Chemical Profile of 1-Bromo-3,5-dimethoxybenzene

This compound, with the molecular formula C8H9BrO2, typically presents as a powder, often white to yellow or light red. Its molecular weight is 217.06. The presence of a bromine atom on the aromatic ring makes it an excellent substrate for nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions. When planning your synthesis, knowing that you can reliably buy 1-Bromo-3,5-dimethoxybenzene with a high assay (e.g., ≥98.0%) from a trusted manufacturer is essential for achieving optimal results.

Key Applications in Synthesis

The most prominent application of 1-Bromo-3,5-dimethoxybenzene is its role as an intermediate in the synthetic preparation of pharmaceutical inhibitors. Its structure is amenable to modifications that lead to the development of drugs targeting specific biological pathways. Furthermore, it is frequently employed in various types of cross-coupling reactions, including:

  • Suzuki-Miyaura Coupling: For forming C-C bonds with boronic acids.
  • Heck Reaction: For coupling with alkenes.
  • Sonogashira Coupling: For coupling with terminal alkynes.

These reactions are cornerstones of modern synthetic chemistry, and a high-quality intermediate like 1-Bromo-3,5-dimethoxybenzene is critical for their success. Researchers often need to purchase 1-Bromo-3,5-dimethoxybenzene to incorporate this specific dimethoxybromobenzene moiety into their target molecules.

Sourcing Strategies and Reliable Suppliers

Finding a dependable supplier for such specialized chemicals is crucial for efficient research and development. Companies looking for the best 1-Bromo-3,5-dimethoxybenzene price often turn to experienced chemical providers, including those based in China, known for their robust manufacturing capabilities and competitive pricing. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier of CAS 20469-65-2, committed to providing high-purity materials to meet your synthesis needs. We ensure that our products are of the quality required for demanding chemical applications.

Conclusion

1-Bromo-3,5-dimethoxybenzene is a valuable asset in the synthetic chemist's toolkit. By understanding its applications and sourcing it from reliable partners, researchers can accelerate their projects and achieve their synthetic goals with greater efficiency and confidence.