In the vast and intricate world of chemical manufacturing, understanding the properties and applications of key intermediates is vital for R&D scientists, product formulators, and procurement managers. 1-Bromo-3-chloropropane (CAS 109-70-6) is one such compound that plays a significant role across various industries, from pharmaceuticals to life sciences. As a dedicated manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide comprehensive insights into this versatile chemical.

Chemical Properties and Appearance

1-Bromo-3-chloropropane is characterized by its clear liquid appearance. Its molecular formula is C3H6BrCl, and it has a molecular weight of approximately 157.44 g/mol. Key physical properties often include:

  • Boiling Point: Around 143-145 °C (at atmospheric pressure).
  • Melting Point: Approximately -59 °C, indicating it remains a liquid under typical laboratory and storage conditions.
  • Density: Around 1.59 g/cm³ at 25 °C, making it denser than water.
  • Solubility: It is insoluble in water but readily soluble in common organic solvents such as ethanol, ether, and chloroform.
  • Flash Point: Varies depending on the source, but typically around 38-81 °C, classifying it as a combustible liquid that requires appropriate handling.

The presence of both bromine and chlorine atoms makes the molecule electrophilic and susceptible to nucleophilic substitution reactions, a property central to its synthetic utility.

Diverse Applications of 1-Bromo-3-chloropropane

The versatility of 1-Bromo-3-chloropropane is evident in its wide range of applications:

  • Pharmaceutical Intermediates: It is a crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug intermediates. It is employed in the pathways for creating medications used to treat cardiovascular diseases and pain, among others.
  • RNA Isolation: It serves as an effective and safer alternative to chloroform for the phase separation step in RNA isolation protocols. This application is critical in molecular biology research, diagnostics, and gene expression studies.
  • Fine Chemical Synthesis: Its reactive nature makes it valuable for constructing a variety of complex organic molecules, including intermediates for agrochemicals, dyes, and specialty materials.
  • Ion Exchange Agents: It is used in the synthesis of compounds that function as ion exchange agents, applicable in water treatment and purification processes.

For those looking to buy this compound, understanding these applications helps in determining the required purity and quantity.

Manufacturer's Perspective: Quality and Supply

As a leading chemical manufacturer and supplier based in China, NINGBO INNO PHARMCHEM CO.,LTD. prioritizes delivering high-purity 1-Bromo-3-chloropropane that meets stringent industry standards. Our production processes are optimized for efficiency and quality control, ensuring lot-to-lot consistency. We understand the critical importance of reliability for our clients, whether they are R&D scientists in a laboratory setting or procurement specialists managing large-scale industrial production. We offer competitive pricing and flexible order quantities, supported by robust logistics and customer service. When you choose us, you are partnering with a reliable source committed to your success. We invite you to inquire for a quote and experience the difference of working with a dedicated chemical provider.

Conclusion

1-Bromo-3-chloropropane is a testament to the power of well-designed chemical intermediates. Its combination of physical properties and chemical reactivity makes it an invaluable asset for innovation in pharmaceuticals, life sciences, and fine chemical industries. By understanding its characteristics and partnering with reputable manufacturers, businesses can ensure they have the necessary materials to drive their projects forward.