The chemical industry constantly evolves, with specialized intermediates playing a pivotal role in the development of new pharmaceuticals, agrochemicals, and advanced materials. One such compound of significant interest is 1-Chlorocarbonyl-3-Methanesulfonyl-2-Imidazolidinone, identified by CAS number 41762-76-9. This article aims to provide B2B stakeholders, including procurement managers and R&D scientists, with a comprehensive understanding of this compound's synthesis, applications, and market dynamics, focusing on its primary role in antibiotic production.

Synthesis and Chemical Properties of CAS 41762-76-9

1-Chlorocarbonyl-3-Methanesulfonyl-2-Imidazolidinone is a complex organic molecule belonging to the imidazolidinone class, featuring a reactive carbonyl chloride group and a methanesulfonyl moiety. Its synthesis typically involves carefully controlled chemical reactions to ensure high purity and desired structural integrity. The compound is commonly presented as a white to off-white powder, with a melting point in the range of 168-173 °C. Its density is approximately 1.71 g/cm³. These physical and chemical properties are critical for its handling, storage, and application in subsequent synthesis steps. For instance, its solubility characteristics in various solvents are important for process chemists to consider when planning reaction conditions.

Primary Application: The Key to Mezlocillin Synthesis

The most prominent application of 1-Chlorocarbonyl-3-Methanesulfonyl-2-Imidazolidinone is its use as a key intermediate in the production of Mezlocillin. Mezlocillin is a potent antibiotic belonging to the ureidopenicillin class, effective against a broad spectrum of Gram-positive and Gram-negative bacteria. The precise introduction of specific chemical functionalities from CAS 41762-76-9 is essential for building the complex molecular structure of Mezlocillin, thereby ensuring its therapeutic effectiveness. Pharmaceutical companies rely heavily on consistent quality and supply of this intermediate to maintain their production schedules and meet global healthcare demands.

Market Trends and Procurement Considerations

The market for pharmaceutical intermediates is dynamic, influenced by factors such as global health trends, regulatory changes, and advancements in synthetic chemistry. The demand for 1-Chlorocarbonyl-3-Methanesulfonyl-2-Imidazolidinone is directly tied to the demand for Mezlocillin and related antibiotics. As a result, reliable sourcing from established manufacturers is crucial. Procurement managers should focus on building relationships with suppliers who can guarantee consistent purity (≥99.0%), offer competitive pricing, and provide robust documentation. Obtaining detailed quotes and comparing offers from various suppliers, particularly those with strong manufacturing capabilities in regions like China, is a standard practice for securing the best value.

As the pharmaceutical industry continues to grow, the role of high-quality intermediates like 1-Chlorocarbonyl-3-Methanesulfonyl-2-Imidazolidinone will remain indispensable. Strategic sourcing and strong supplier partnerships are key to navigating this complex market successfully.