For R&D scientists and product formulators, understanding the applications and reliable sourcing of key chemical intermediates like 1-Chloroisoquinoline-4-carbonitrile (CAS No.: 53491-80-8) is crucial for innovation. This article delves into the compound's utility and provides insights for procurement professionals looking to buy from reputable suppliers.

The Versatility of 1-Chloroisoquinoline-4-carbonitrile in Synthesis

1-Chloroisoquinoline-4-carbonitrile is a highly valuable intermediate in the realm of organic chemistry. Its unique structural features, particularly the chlorine atom and the carbonitrile group attached to an isoquinoline core, make it an excellent starting material for a wide array of synthetic transformations. Its primary applications include:

  • Pharmaceutical Drug Discovery: As a building block, it is instrumental in synthesizing complex heterocyclic scaffolds that are prevalent in many active pharmaceutical ingredients (APIs). Researchers often look to buy this compound for creating novel drug candidates.
  • Agrochemical Development: The isoquinoline framework can be found in certain agrochemicals, and this intermediate provides a pathway to explore new active ingredients for crop protection.
  • Material Science: Its structure can be modified to create advanced materials with specific electronic or optical properties, such as those used in OLEDs or other optoelectronic devices.
  • Research and Development: It serves as a fundamental reagent in academic and industrial laboratories for exploring new reaction methodologies and synthesizing target molecules.

Ensuring Quality When You Buy

When sourcing 1-Chloroisoquinoline-4-carbonitrile, particularly from international markets like China, prioritizing quality is non-negotiable. The specified purity of 97% minimum is a key indicator of its suitability for synthesis. Reputable manufacturers will provide detailed Certificates of Analysis (CoA) and ensure consistency in their production batches.

Where to Find Reliable Suppliers

Identifying a trustworthy manufacturer or supplier for 1-Chloroisoquinoline-4-carbonitrile is vital. Look for suppliers who:

  • Clearly list the CAS number (53491-80-8) and purity (e.g., 97% min).
  • Offer competitive pricing and are willing to provide quotes for your required quantities.
  • Have a responsive customer service team to address your inquiries and facilitate the purchase.
  • Provide options for sample orders to verify quality before committing to larger quantities.

Engaging with a dedicated chemical supplier, especially one with a strong presence in China, can provide access to this essential intermediate at favorable terms. They act as a crucial link between the manufacturing capabilities and the end-users, ensuring that your procurement process is smooth and efficient.