In the dynamic field of chemical manufacturing, understanding the properties and applications of key intermediates is crucial for research, development, and production. 1-Methanesulfonyl-2-imidazolidinone (CAS 41730-79-4) stands out as a significant compound, primarily recognized for its role in pharmaceutical synthesis. This article provides a detailed look at its characteristics, its essential applications, and a practical guide for sourcing it from reliable manufacturers and suppliers.

Chemical Profile of 1-Methanesulfonyl-2-imidazolidinone

1-Methanesulfonyl-2-imidazolidinone is chemically defined by its molecular formula C4H8N2O3S and a molecular weight of approximately 164.18 g/mol. Key physical and chemical properties include:

  • Appearance: A clean White crystalline powder.
  • Purity: Typically specified as ≥99.0% by GC or HPLC, ensuring high quality for sensitive applications.
  • Melting Point: Generally ranges between 188-190°C, indicating its solid state and thermal stability under normal conditions.
  • CAS Number: 41730-79-4.
  • Synonyms: Includes 1-(Methylsulfonyl)-2-imidazolidinone, 1-Methanesulfonyl-2-imidazolidinone, among others, which are useful for broader searches when you buy.

These properties make it a stable and easily handled intermediate for chemical synthesis.

Primary Application: Intermediate for Mezlocillin Sodium

The most prominent application of 1-Methanesulfonyl-2-imidazolidinone is its function as a vital intermediate in the synthesis of Mezlocillin sodium. Mezlocillin is a potent, broad-spectrum antibiotic belonging to the ureidopenicillin class. Its efficacy against severe bacterial infections necessitates the use of high-purity precursors like 1-Methanesulfonyl-2-imidazolidinone to ensure the safety and effectiveness of the final API. Pharmaceutical companies looking to manufacture Mezlocillin sodium must secure a consistent and high-quality source for this intermediate.

Exploring Other Potential Applications

While its role in Mezlocillin sodium synthesis is well-established, the unique chemical structure of 1-Methanesulfonyl-2-imidazolidinone suggests potential applications in broader organic synthesis. Its heterocyclic nature and the presence of sulfonyl and amide functionalities could make it a valuable building block for:

  • Developing novel pharmaceutical agents.
  • Synthesizing specialty chemicals with tailored properties.
  • Research into new agrochemical compounds.

Researchers interested in exploring these avenues can purchase this compound from chemical suppliers for R&D purposes.

Sourcing Strategies: Finding the Best Price and Suppliers

Procuring 1-Methanesulfonyl-2-imidazolidinone requires a strategic approach:

  • Identify Reliable Manufacturers: Seek out companies with proven expertise in producing pharmaceutical intermediates. Many leading manufacturers are based in China, offering competitive pricing and scalable production.
  • Verify Purity and Specifications: Always request a Certificate of Analysis (CoA) and ensure the purity meets your requirements (e.g., ≥99.0%).
  • Compare Price Quotes: Obtain quotes from multiple suppliers to ensure you are getting the best market price. Consider long-term supply agreements for better rates.
  • Assess Lead Times and Logistics: Ensure the supplier can meet your delivery schedule.
  • Request Samples: Before committing to large orders, test samples to confirm quality and suitability.

Working with a reputable supplier in China can often provide a balance of quality and cost-effectiveness. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to providing high-quality chemical products and intermediates. When you choose to buy from us, you benefit from our commitment to excellence and reliable supply chains.

Conclusion

1-Methanesulfonyl-2-imidazolidinone is an indispensable compound in the pharmaceutical industry, vital for the synthesis of Mezlocillin sodium. Its well-defined properties and high purity make it a preferred choice for manufacturers. By employing effective sourcing strategies and partnering with credible manufacturers, companies can secure a reliable supply of this critical intermediate, ensuring the continuous production of essential medications.