1-Methyl-L-histidine: Key Chemical Properties and Applications
1-Methyl-L-histidine, identified by CAS number 332-80-9, is a fascinating derivative of the naturally occurring amino acid L-histidine. Characterized by a methyl group attached to one of the nitrogen atoms in the imidazole ring, this compound exhibits distinct chemical properties that lend themselves to a variety of specialized applications. Understanding these properties is fundamental for researchers and formulators looking to leverage its unique attributes. As a reputable manufacturer and supplier, we are committed to providing high-quality 1-Methyl-L-histidine for diverse industrial and research needs.
Chemically, 1-Methyl-L-histidine (molecular formula C7H11N3O2, molecular weight 169.18 g/mol) typically presents as an off-white to pale beige solid. Its melting point is noted to be around 240 °C with decomposition, indicating its thermal stability within a certain range. Solubility in common solvents like methanol and water is described as slight, which can be a critical factor in formulation development. The optical activity, often measured as [α]20/D, around -24°, further defines its stereochemistry, a crucial aspect for biological applications.
The applications of 1-Methyl-L-histidine are broad and growing. In research, it is explored as a potential biomarker for conditions such as inflammation and muscle toxicity, particularly its elevated levels in conditions like diabetes. This makes it a valuable tool for diagnostic development and understanding metabolic pathways. For chemical synthesis, it serves as a useful building block, particularly in the creation of more complex molecules for pharmaceutical research. As a non-proteinogenic amino acid, its unique structure can be incorporated into peptides or other organic compounds to impart specific characteristics or functionalities.
For those looking to purchase 1-Methyl-L-histidine, it is essential to partner with a reliable manufacturer and supplier. We offer this compound with assured purity and in compliance with various quality standards, ensuring its suitability for sensitive research and development projects. Whether you need it for enzymatic studies, as a reference standard, or as an intermediate in synthetic chemistry, our competitively priced 1-Methyl-L-histidine is available to meet your demands. We encourage you to inquire about our product specifications, pricing for bulk orders, and to request a quote for your specific requirements.
Perspectives & Insights
Future Origin 2025
“Its melting point is noted to be around 240 °C with decomposition, indicating its thermal stability within a certain range.”
Core Analyst 01
“Solubility in common solvents like methanol and water is described as slight, which can be a critical factor in formulation development.”
Silicon Seeker One
“The optical activity, often measured as [α]20/D, around -24°, further defines its stereochemistry, a crucial aspect for biological applications.”