1-Methylindazole-3-carboxylic Acid: Properties, Production, and Supply Chain Insights
1-Methylindazole-3-carboxylic acid, a compound identified by CAS number 50890-83-0, plays a vital role in the pharmaceutical industry as a key intermediate for Granisetron synthesis. This article provides insights into its properties, production, packaging, and the global supply chain dynamics from the perspective of a leading manufacturer. Understanding these aspects is crucial for anyone involved in sourcing or utilizing this important pharmaceutical building block.
Chemically, 1-Methylindazole-3-carboxylic acid is characterized by its white to off-white crystalline powder appearance. Its molecular formula is C9H8N2O2, with a molecular weight of approximately 176.17 g/mol. Key physical properties include a high melting point, typically in the range of 213-218°C, and solubility in methanol, which is advantageous for its use in various organic synthesis reactions. These properties are carefully controlled during its production to ensure high purity, often exceeding 99%, and minimal levels of impurities.
The production of 1-Methylindazole-3-carboxylic acid involves complex organic synthesis processes. Manufacturers prioritize precision in reaction conditions, purification techniques, and quality control to meet stringent pharmaceutical standards. Once synthesized, the compound is typically packaged in 25kg cardboard drums, though custom packaging solutions are available to meet specific client requirements. Storage recommendations emphasize keeping the compound in a cool, dry place, in a well-closed container, to maintain its stability and integrity over time.
The supply chain for pharmaceutical intermediates like 1-Methylindazole-3-carboxylic acid is global and highly regulated. China has emerged as a significant hub for its production, owing to its robust chemical manufacturing sector, technological advancements, and competitive pricing. Companies like NINGBO INNO PHARMCHEM CO.,LTD. leverage these advantages to supply high-quality intermediates to the pharmaceutical industry worldwide. Ensuring a reliable and consistent supply chain is paramount, as delays or quality issues can significantly impact drug manufacturing timelines and patient access to essential medications.
The market demand for 1-Methylindazole-3-carboxylic acid is closely linked to the demand for Granisetron, an antiemetic drug crucial for managing nausea and vomiting in patients undergoing chemotherapy or radiotherapy. Therefore, manufacturers focus on scalability and efficiency to meet this demand. By understanding the chemical properties, production nuances, and supply chain considerations, pharmaceutical companies can make informed decisions when sourcing this critical intermediate, ensuring the successful and high-quality production of vital medicines.
Chemically, 1-Methylindazole-3-carboxylic acid is characterized by its white to off-white crystalline powder appearance. Its molecular formula is C9H8N2O2, with a molecular weight of approximately 176.17 g/mol. Key physical properties include a high melting point, typically in the range of 213-218°C, and solubility in methanol, which is advantageous for its use in various organic synthesis reactions. These properties are carefully controlled during its production to ensure high purity, often exceeding 99%, and minimal levels of impurities.
The production of 1-Methylindazole-3-carboxylic acid involves complex organic synthesis processes. Manufacturers prioritize precision in reaction conditions, purification techniques, and quality control to meet stringent pharmaceutical standards. Once synthesized, the compound is typically packaged in 25kg cardboard drums, though custom packaging solutions are available to meet specific client requirements. Storage recommendations emphasize keeping the compound in a cool, dry place, in a well-closed container, to maintain its stability and integrity over time.
The supply chain for pharmaceutical intermediates like 1-Methylindazole-3-carboxylic acid is global and highly regulated. China has emerged as a significant hub for its production, owing to its robust chemical manufacturing sector, technological advancements, and competitive pricing. Companies like NINGBO INNO PHARMCHEM CO.,LTD. leverage these advantages to supply high-quality intermediates to the pharmaceutical industry worldwide. Ensuring a reliable and consistent supply chain is paramount, as delays or quality issues can significantly impact drug manufacturing timelines and patient access to essential medications.
The market demand for 1-Methylindazole-3-carboxylic acid is closely linked to the demand for Granisetron, an antiemetic drug crucial for managing nausea and vomiting in patients undergoing chemotherapy or radiotherapy. Therefore, manufacturers focus on scalability and efficiency to meet this demand. By understanding the chemical properties, production nuances, and supply chain considerations, pharmaceutical companies can make informed decisions when sourcing this critical intermediate, ensuring the successful and high-quality production of vital medicines.
Perspectives & Insights
Chem Catalyst Pro
“Once synthesized, the compound is typically packaged in 25kg cardboard drums, though custom packaging solutions are available to meet specific client requirements.”
Agile Thinker 7
“Storage recommendations emphasize keeping the compound in a cool, dry place, in a well-closed container, to maintain its stability and integrity over time.”
Logic Spark 24
“The supply chain for pharmaceutical intermediates like 1-Methylindazole-3-carboxylic acid is global and highly regulated.”