In the realm of organic chemistry and pharmaceutical development, specific molecular building blocks are indispensable for creating novel compounds. 2-(3-Chlorophenyl)-1,3-thiazole-4-carboxylic acid, identified by CAS number 845885-82-7, is one such critical intermediate. Its unique chemical structure makes it a valuable component in various synthesis routes, particularly for drug discovery and the development of advanced materials. Understanding its properties and applications is key for any scientist or procurement specialist looking to buy this chemical.

Chemical Identity and Physical Characteristics

2-(3-Chlorophenyl)-1,3-thiazole-4-carboxylic acid is an organosulfur compound featuring a thiazole ring substituted with a chlorophenyl group and a carboxylic acid moiety. Its molecular formula is C10H6ClNO2S, with a molecular weight of approximately 239.68 g/mol. Physically, it is typically observed as a white powder, a common form for many fine chemical intermediates. A notable physical characteristic is its melting point, which is reported to be around 206°C. This high melting point suggests a stable crystalline structure, beneficial for handling and storage.

Applications in Chemical Synthesis

The utility of 2-(3-Chlorophenyl)-1,3-thiazole-4-carboxylic acid lies in its versatile reactivity. The carboxylic acid group can be readily converted into esters, amides, or acid halides, enabling its coupling with various amines, alcohols, or other nucleophiles. The thiazole ring itself, with its heteroatoms, offers sites for further functionalization or can act as a pharmacophore in biologically active molecules.

  • Pharmaceutical Intermediates: This compound serves as a crucial precursor in the synthesis of various pharmaceutical agents. Its structure can be incorporated into molecules designed to target specific biological pathways, making it a sought-after building block in drug discovery programs. Researchers looking to buy this for API synthesis will value its defined purity.
  • Agrochemicals: While primarily recognized for pharmaceutical applications, similar heterocyclic structures are also found in certain agrochemical compounds, suggesting potential applications in this sector as well.
  • Materials Science: The unique electronic properties of thiazole derivatives can also lend themselves to applications in materials science, such as in the development of organic semiconductors or dyes.

Procurement Considerations

When sourcing 2-(3-Chlorophenyl)-1,3-thiazole-4-carboxylic acid, it is essential to partner with reliable manufacturers and suppliers. Purchasing this intermediate from a reputable source in China ensures access to high-quality material, competitive pricing, and consistent supply, which are all critical for efficient laboratory research and industrial production. Whether you are a research scientist needing small quantities for initial studies or a procurement manager securing bulk orders, understanding the chemical's specifications and its role in synthesis is key to successful acquisition.

As a leading manufacturer and supplier, we are committed to providing chemists and pharmaceutical developers with this vital building block. We ensure that our 2-(3-Chlorophenyl)-1,3-thiazole-4-carboxylic acid meets the high standards required for advanced synthesis projects.