For professionals in the chemical and pharmaceutical industries, a thorough understanding of chemical intermediates is vital for successful product development and manufacturing. 2,3-Cyclopentenopyridine, identified by CAS number 533-37-9, is one such critical compound. This heterocyclic molecule is characterized by its fused cyclopentane and pyridine ring structure, offering unique chemical properties that make it invaluable in a variety of advanced applications. Sourcing this material requires attention to its technical specifications and reliable supplier relationships.

Key Technical Specifications of 2,3-Cyclopentenopyridine

2,3-Cyclopentenopyridine (chemical formula: C8H9N, molecular weight: 119.16 g/mol) is typically described as a clear, colorless to brownish liquid at standard conditions. Its physical properties, such as a flash point of around 67-70°C and a density of approximately 1.018 g/mL at 25°C, are important considerations for handling, storage, and process design. The purity of the compound is paramount, with suppliers often offering grades of ≥99% for demanding applications, particularly in pharmaceutical synthesis.

Applications and Chemical Utility

The chemical utility of 2,3-Cyclopentenopyridine is diverse. It serves as a vital intermediate in the pharmaceutical industry, notably in the synthesis of cefpirome, a broad-spectrum cephalosporin antibiotic. Its role as a reactant in ruthenium-mediated dual catalytic reactions, including C-H activation and dearomatization for isoquinolone synthesis, highlights its importance in modern organic chemistry. Furthermore, it is utilized in the agrochemical sector for the development of plant protective agents and in the creation of specialized synthetic resins.

Sourcing Strategies and Supplier Engagement

When looking to buy 2,3-Cyclopentenopyridine, establishing connections with reputable manufacturers and suppliers is crucial. Companies often seek out partners based in China due to the country's strong chemical manufacturing infrastructure, which can offer competitive pricing and a consistent supply of high-quality intermediates. Procurement managers should focus on suppliers who provide detailed product data, including CAS numbers, purity assays, and safety information.

Requesting detailed quotes for bulk purchases is a standard practice to manage costs effectively. Understanding the available packaging options and delivery terms from suppliers is also important for seamless integration into production workflows. For research and development purposes, smaller quantities are readily available, allowing for initial testing and validation.

In summary, 2,3-Cyclopentenopyridine is a compound of significant value in advanced chemical synthesis. By focusing on its technical specifications and engaging with reliable manufacturers and suppliers, businesses can ensure they are well-equipped to leverage its unique properties for innovation across pharmaceuticals, catalysis, and material science.