In the dynamic field of chemical manufacturing, intermediates that offer both versatility and specific reactivity are highly prized. 2-Amino-3-bromobenzoic Acid (CAS: 20776-51-6) stands out as such a compound, playing a crucial role in various industrial processes, particularly in pharmaceutical development and fine chemical synthesis. As a dedicated chemical enterprise, we are pleased to share our expertise on this important molecule.

The synthesis of 2-Amino-3-bromobenzoic Acid typically involves the controlled electrophilic bromination of 2-aminobenzoic acid (anthranilic acid). Achieving regioselectivity, specifically directing the bromine atom to the 3-position, is a key aspect of its efficient production. Our manufacturing processes are designed to yield this compound with high purity, often exceeding 98%, presenting as a fine white powder. The molecular formula is C7H6BrNO2, and its molecular weight is approximately 216.03 g/mol. Its relatively high melting point underscores its stability as a solid intermediate.

The chemical properties of 2-Amino-3-bromobenzoic Acid make it a valuable synthon. The presence of an amino group allows for transformations such as diazotization and acylation. The carboxylic acid group readily undergoes esterification and amide formation. Crucially, the bromine atom on the aromatic ring serves as an excellent leaving group or a site for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling the introduction of diverse substituents and the construction of complex molecular architectures. This reactivity is fundamental to its use as a building block.

The industrial applications of 2-Amino-3-bromobenzoic Acid are primarily concentrated in the pharmaceutical sector, where it acts as a key intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its derivatives have shown promise in areas such as antimicrobial agents, anti-inflammatory compounds, and potential anticancer therapeutics. Beyond pharmaceuticals, it is also utilized in the synthesis of specialized dyes and pigments, and in polymer chemistry to enhance material properties. For businesses looking to buy this intermediate, understanding these applications highlights its commercial significance.

As a leading manufacturer and supplier, we are committed to delivering consistent quality and reliability. We offer competitive wholesale pricing and efficient global logistics to support your production needs. If your organization requires 2-Amino-3-bromobenzoic Acid, we invite you to connect with us for detailed product specifications, current pricing, and to discuss your specific requirements. Partnering with a reputable supplier ensures the integrity and success of your chemical projects.