The pharmaceutical industry is in constant pursuit of innovative treatments, a journey that heavily relies on the availability of specialized chemical building blocks. Among these, 2-Amino-5-bromobenzophenone (CAS 39859-36-4) stands out as a particularly valuable compound. Its unique chemical structure makes it an indispensable intermediate in the synthesis of a wide array of pharmacologically active molecules. For researchers engaged in drug discovery, understanding the properties and applications of this compound is key to unlocking new therapeutic possibilities.

The Chemical Profile of 2-Amino-5-bromobenzophenone

With the CAS number 39859-36-4, this benzophenone derivative, characterized by the molecular formula C13H10BrNO, is a versatile reagent. It typically presents as a light yellow to off-white powder, with a guaranteed purity of 98% or higher. The presence of both an amine group and a bromine atom on the benzophenone core provides strategic handles for various chemical transformations. This allows chemists to introduce diverse substituents and build complex molecular architectures essential for drug candidates.

Applications in Drug Discovery and Development

The primary utility of 2-Amino-5-bromobenzophenone lies in its role as a precursor for synthesizing Active Pharmaceutical Ingredients (APIs). Its structure facilitates key reactions, including:

  • Heterocyclic Synthesis: It is often used in the construction of nitrogen-containing heterocyclic ring systems, which are prevalent in many drug classes.
  • Coupling Reactions: The bromine atom allows for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), enabling the formation of new carbon-carbon or carbon-nitrogen bonds.
  • Amine Functionalization: The amino group can be further modified through acylation, alkylation, or other reactions to tailor the properties of the final molecule.

By utilizing this intermediate, researchers can efficiently develop novel compounds with potential activity against a range of diseases, from oncology and infectious diseases to neurological disorders.

Procurement for Research: Finding a Reliable Supplier

For research institutions and pharmaceutical companies, sourcing high-quality 2-Amino-5-bromobenzophenone is crucial. While many international suppliers exist, the competitive landscape often leads buyers to consider manufacturers in regions like China. When seeking to buy this intermediate for research purposes, it's important to look for suppliers who can guarantee:

  • High Purity: For drug discovery, even small impurities can significantly impact experimental results. A purity of >=98% is often a minimum requirement.
  • Consistent Quality: Batch-to-batch consistency is essential for reproducible research.
  • Availability and Lead Times: Researchers often work under tight deadlines. Prompt delivery is a key factor.
  • Competitive Price: While research quantities may be smaller, cost-effectiveness remains important, especially for extensive screening programs.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of fine chemicals and pharmaceutical intermediates. We provide researchers with access to quality compounds like 2-Amino-5-bromobenzophenone, understanding the critical role these materials play in advancing scientific discovery. If you are looking to purchase this essential intermediate, we offer reliable sourcing and competitive pricing. Partner with us to accelerate your drug discovery initiatives.