For organic chemists, the availability of reliable and versatile building blocks is the cornerstone of successful synthesis. 2-Bromo-5-fluorobenzoic acid (CAS: 394-28-5) is one such indispensable compound, prized for its unique combination of functional groups—a carboxylic acid, a bromine atom, and a fluorine atom—which unlock a vast array of synthetic possibilities. As a dedicated manufacturer and supplier, we provide this crucial intermediate to researchers and chemists worldwide, supporting advancements across various chemical disciplines.

The utility of 2-Bromo-5-fluorobenzoic acid in organic synthesis stems from its distinct reactivity. The carboxylic acid group can undergo standard transformations like esterification, amidation, or reduction. More significantly, the bromine atom is an excellent handle for palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are foundational for constructing complex carbon-carbon bonds, enabling the synthesis of biaryls, substituted alkenes, and alkynes—structures prevalent in pharmaceuticals, agrochemicals, and advanced materials. The fluorine atom, a key feature in many modern bioactive molecules, can modulate electronic properties, enhance metabolic stability, and influence receptor binding.

Understanding its synthesis is crucial for any chemist. While various routes exist, including direct bromination of fluorobenzoic acid derivatives, our manufacturing processes ensure high purity (typically ≥99.0%) and consistent quality. This allows chemists to reliably buy 2-Bromo-5-fluorobenzoic acid and integrate it seamlessly into their synthetic strategies. Whether you need it for fragment-based drug discovery, creating novel fluorinated compounds, or building complex heterocyclic systems, this intermediate offers exceptional flexibility.

The competitive price and stable supply chain we offer, as a direct supplier in China, further empower chemists to utilize this versatile compound in both small-scale research and larger synthetic projects. We are committed to supporting the scientific community by providing high-quality materials that accelerate discovery and innovation.

In conclusion, for chemists aiming to push the boundaries of organic synthesis, 2-Bromo-5-fluorobenzoic acid is an invaluable asset. We encourage you to consider our reliable supply for your next synthetic endeavor. Contact us to discuss your requirements and to access this essential building block.