In the complex landscape of chemical manufacturing and research, specific intermediates stand out for their versatility and importance. 2-Bromo-5-methoxyaniline (CAS: 59557-92-5) is one such compound, playing a vital role in both pharmaceutical development and the burgeoning field of OLED technology. For R&D scientists and product formulators, understanding its characteristics, synthesis, and industrial utility is key to successful project execution and sourcing.

Chemical Profile and Properties

2-Bromo-5-methoxyaniline is an organic chemical with the molecular formula C7H8BrNO and a molecular weight of 202.05. It is characterized by its chemical structure, which features a bromine atom and a methoxy group attached to an aniline ring. The reported melting point is in the range of 189-190°C, and it often presents as a brown solid or liquid. This compound is also identified by CAS number 59557-92-5, a crucial identifier for procurement and regulatory purposes. When you consider the price of this chemical, understanding its purity, typically around 97-98%, is essential for matching it to your specific application needs.

Synthesis Pathways and Manufacturing Insights

The synthesis of 2-Bromo-5-methoxyaniline often involves multi-step processes starting from readily available precursors. A common synthetic route involves the reduction of 4-bromo-3-nitroanisole. This reduction is typically carried out using reagents like iron powder in the presence of ammonium chloride, followed by reaction with sodium nitrite to form a diazonium salt, and subsequent chemical transformations. Manufacturers focus on optimizing these routes to achieve high yields and purity, ensuring that the product is suitable for demanding downstream applications. For any company looking to buy this intermediate, understanding the manufacturing process can provide insights into potential impurities and quality control measures.

Industrial Applications Driving Demand

The demand for 2-Bromo-5-methoxyaniline is significantly driven by its critical role in:

  • Pharmaceutical Intermediates: It is a foundational chemical for synthesizing complex drug molecules. Its structure allows for further functionalization, making it a valuable building block for therapeutic agents targeting conditions like cancer (e.g., EGFR inhibitors) and various other diseases. Research chemists often seek reliable suppliers of this intermediate for their drug discovery programs.
  • OLED Technology: As the electronics industry pushes for more advanced display and lighting solutions, intermediates like 2-Bromo-5-methoxyaniline are indispensable. It contributes to the synthesis of specialized organic materials that form the light-emitting layers in OLED panels. Manufacturers in this sector depend on consistent quality from their chemical manufacturers.

For industries requiring this compound, engaging with a reputable chemical supplier is key. Whether for bulk procurement or specialized research quantities, understanding the product's origin, quality control, and pricing is vital. By partnering with experienced chemical providers, businesses can ensure they obtain the necessary raw materials to drive innovation and maintain competitive advantage.