2-Bromo-6-fluoroaniline: Synthesis Applications and Market Trends
The chemical industry is continuously evolving, driven by demand for specialized molecules that enable advancements in pharmaceuticals, agrochemicals, and material science. Among the vast array of chemical intermediates, 2-Bromo-6-fluoroaniline (CAS 65896-11-9) has gained significant prominence due to its versatile synthetic utility. As a manufacturer and supplier, we provide a comprehensive understanding of this compound's applications and the market dynamics that influence its procurement, especially for businesses looking to buy from reliable global sources.
2-Bromo-6-fluoroaniline is a halogenated aromatic amine characterized by its specific molecular configuration. The presence of both bromine and fluorine atoms on the aniline ring imparts unique reactivity, making it a valuable building block in organic synthesis. The bromine atom is adept at participating in palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings, which are essential for constructing complex carbon-carbon and carbon-heteroatom bonds. The fluorine atom, on the other hand, is known to influence the electronic properties, lipophilicity, and metabolic stability of molecules. This dual functionality makes 2-Bromo-6-fluoroaniline a critical intermediate for medicinal chemists and materials scientists aiming to design compounds with specific biological or physical properties.
In the pharmaceutical sector, the demand for high-purity intermediates is paramount. 2-Bromo-6-fluoroaniline, typically supplied at purity levels of 97% or higher, is widely used in the synthesis of Active Pharmaceutical Ingredients (APIs). Its incorporation into drug molecules can lead to enhanced therapeutic efficacy, improved pharmacokinetic profiles, and better binding affinities to target receptors. For researchers and procurement managers, securing a consistent supply of this intermediate from trusted manufacturers is crucial for accelerating drug discovery and development pipelines. The global market for such intermediates often sees competitive pricing from suppliers in regions like China, making it an attractive option for bulk purchases.
The applications of 2-Bromo-6-fluoroaniline extend beyond pharmaceuticals to the fine chemical industry. It is employed in the formulation of advanced agrochemicals, contributing to the development of novel herbicides and pesticides that offer improved efficacy and environmental profiles. In material science, it can be utilized in the synthesis of specialty polymers, dyes, and optoelectronic materials, where its unique structural features impart desired performance characteristics. The physical properties of 2-Bromo-6-fluoroaniline, such as its clear yellow to brown liquid appearance and a molecular weight of approximately 190.01 g/mol, are important considerations for its industrial handling and use.
Understanding market trends and ensuring a reliable supply chain are key to successful chemical procurement. We are dedicated to providing high-quality 2-Bromo-6-fluoroaniline and supporting our clients with their synthesis needs. We encourage interested parties to inquire about our product specifications, pricing, and bulk order capabilities. Partner with us to secure a dependable source for this essential chemical intermediate and drive your innovation forward.
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“The chemical industry is continuously evolving, driven by demand for specialized molecules that enable advancements in pharmaceuticals, agrochemicals, and material science.”