2-Bromo-7-hydroxynaphthalene: A Key Building Block for Organic Chemistry
Organic chemistry is a field driven by the manipulation of molecular structures to create new compounds with desired properties. At the heart of this discipline are versatile chemical building blocks, and 2-Bromo-7-hydroxynaphthalene (CAS: 116230-30-9) stands out as a significant example. Also recognized as 7-Bromo-2-naphthol, this compound offers chemists a unique combination of reactive sites, making it indispensable for a wide array of synthetic pathways. For researchers and chemical manufacturers, understanding its potential and securing a reliable supply chain is crucial.
The Versatility of 2-Bromo-7-hydroxynaphthalene in Synthesis
The chemical structure of 2-Bromo-7-hydroxynaphthalene, with its naphthalene backbone, a bromine atom at the 2-position, and a hydroxyl group at the 7-position, endows it with significant synthetic utility. This arrangement allows for diverse reactions such as:
- Electrophilic Aromatic Substitution: The electron-donating hydroxyl group activates the aromatic rings for further functionalization.
- Nucleophilic Substitution: The bromine atom can be displaced by various nucleophiles, facilitating the introduction of new functional groups.
- Coupling Reactions: The aryl bromide moiety is amenable to palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling the formation of carbon-carbon bonds.
These reactive properties make it a valuable starting material for synthesizing complex organic molecules, including advanced intermediates for pharmaceuticals, materials science, and specialty chemicals. When purchasing this compound, it is important to source it from manufacturers who guarantee high purity (typically 97% min), ensuring predictable and efficient reaction outcomes.
Sourcing Strategies for Organic Chemists
For scientists and procurement professionals looking to buy 2-Bromo-7-hydroxynaphthalene, several strategies are advisable:
- Identify Reputable Manufacturers: Partnering with established chemical suppliers, particularly those based in regions with strong chemical manufacturing capabilities like China, can provide access to quality products at competitive prices.
- Request Detailed Specifications: Always ask for a Certificate of Analysis (CoA) to confirm the purity, CAS number (116230-30-9), and physical form (e.g., white crystalline powder) meet your project's needs.
- Consider Bulk Purchases: If your laboratory or company has ongoing synthesis projects, purchasing 7-Bromo-2-naphthol in larger quantities often leads to better pricing and ensures a consistent supply. Obtaining a formal quote is a necessary step.
- Evaluate Lead Times: Factor in production and shipping times, especially for international orders, to ensure timely delivery for your research timelines.
The availability of high-quality 2-Bromo-7-hydroxynaphthalene empowers chemists to push the boundaries of molecular design and synthesis. By selecting a reliable supplier, you can ensure your organic chemistry endeavors are supported by the best available building blocks, contributing to innovation and efficiency in your work.
Perspectives & Insights
Bio Analyst 88
“The Versatility of 2-Bromo-7-hydroxynaphthalene in SynthesisThe chemical structure of 2-Bromo-7-hydroxynaphthalene, with its naphthalene backbone, a bromine atom at the 2-position, and a hydroxyl group at the 7-position, endows it with significant synthetic utility.”
Nano Seeker Pro
“This arrangement allows for diverse reactions such as:Electrophilic Aromatic Substitution: The electron-donating hydroxyl group activates the aromatic rings for further functionalization.”
Data Reader 7
“Nucleophilic Substitution: The bromine atom can be displaced by various nucleophiles, facilitating the introduction of new functional groups.”