The intricate world of pharmaceutical research and development relies heavily on the availability of precisely manufactured chemical building blocks. Among these, 2-Butyl-4-chloro-5-formylimidazole, identified by CAS number 83857-96-9, holds a significant position. Its unique molecular structure and chemical properties make it an invaluable intermediate, particularly in the synthesis of complex APIs like Losartan, a widely used medication for managing hypertension and related cardiovascular conditions.

Understanding the chemical profile of 2-Butyl-4-chloro-5-formylimidazole is essential for researchers and formulators. Typically appearing as a little-yellow crystalline powder, its purity levels are critical, with manufacturers often guaranteeing assays of 98.0% to 101.0%. This high purity is vital for minimizing side reactions and ensuring the efficacy and safety of the final pharmaceutical product. Key physical and chemical properties, such as its melting point (around 97-100 °C), solubility in common organic solvents like methanol and ethanol, and its density, are important considerations for process chemists and formulation scientists.

The primary application of this compound is its use as an intermediate in the synthesis of Losartan, a potent angiotensin II receptor blocker. However, its utility extends to the broader development of other N-(biphenylylmethyl)imidazoles, a class of compounds that act as angiotensin II antagonists. For R&D teams exploring new cardiovascular therapies or seeking to improve existing drug synthesis routes, securing a reliable supply of high-quality 2-Butyl-4-chloro-5-formylimidazole is paramount. Access to this intermediate allows for experimentation with novel synthetic pathways and the development of next-generation pharmaceuticals.

For those looking to buy this essential chemical, partnering with a reputable manufacturer and supplier is key. Companies that specialize in pharmaceutical intermediates often offer detailed product documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), which are indispensable for quality control and regulatory compliance. Furthermore, competitive pricing and dependable supply chains, particularly from manufacturers in China, are significant factors for bulk purchasing and large-scale production needs.

In essence, 2-Butyl-4-chloro-5-formylimidazole (CAS 83857-96-9) serves as a testament to the importance of specialized chemical intermediates in advancing pharmaceutical science. Its role in creating vital medicines like Losartan, and its potential in future drug discovery, solidify its status as a crucial building block for innovation within the pharmaceutical industry.