In the landscape of fine chemicals, intermediates with unique functional groups are highly prized for their versatility. 2-Chloro-3-hydroxy-4-methoxybenzaldehyde (CAS 37687-57-3) is one such compound, playing a vital role in the pharmaceutical and fragrance industries. For businesses looking to procure this essential chemical, understanding its synthesis, applications, and how to find reliable suppliers is paramount.

Synthesis and Chemical Profile

The production of 2-Chloro-3-hydroxy-4-methoxybenzaldehyde typically involves chemical synthesis, often starting from isovanillin. A common synthetic pathway involves electrophilic chlorination under controlled conditions to introduce the chlorine atom at the desired position on the aromatic ring. The resulting compound, characterized by its aldehyde, hydroxyl, methoxy, and chloro substituents, offers reactive sites for further chemical transformations.

Key specifications to verify when you buy 2-Chloro-3-hydroxy-4-methoxybenzaldehyde include its high purity (≥99.0%), appearance (white powder), and melting point (204-208 °C). These parameters are critical indicators of quality, especially for sensitive applications.

Key Industrial Applications

The demand for this chemical intermediate stems from its crucial roles:

  • Pharmaceutical Intermediates: It is frequently used as a starting material or intermediate in the synthesis of complex pharmaceutical compounds, including those with potential therapeutic benefits.
  • Fragrance and Perfume Ingredients: The compound's chemical structure imparts specific aromatic qualities, making it valuable in the formulation of perfumes and other scented products.
  • Organic Synthesis Reagent: Researchers and industrial chemists utilize it as a versatile building block in various organic reactions to create novel molecules.

Sourcing Strategies for Procurement Managers

When seeking to purchase 2-Chloro-3-hydroxy-4-methoxybenzaldehyde, it is advisable to engage with reputable chemical suppliers. Here are some tips for effective sourcing:

  • Identify Direct Manufacturers: Partnering with a direct manufacturer can provide access to better pricing and more consistent quality control. For example, a trusted 2-Chloro-3-hydroxy-4-methoxybenzaldehyde supplier in China can be a strategic partner.
  • Request Quotes and Samples: Always request detailed quotes, including the price of 2-Chloro-3-hydroxy-4-methoxybenzaldehyde, and order samples to verify quality before placing a bulk order.
  • Verify Quality Assurance: Confirm that the supplier adheres to international quality standards and can provide necessary documentation like COAs.

By understanding the synthesis, applications, and employing strategic sourcing practices, businesses can efficiently procure high-quality 2-Chloro-3-hydroxy-4-methoxybenzaldehyde to meet their manufacturing and R&D objectives.