The continuous pursuit of effective treatments for complex diseases like osteoporosis demands innovative chemical solutions and reliable intermediates. Among these, 2-Cyanopyrimidine (CAS 14080-23-0) has carved out a significant niche, primarily due to its potent inhibitory action against Cathepsin K. As a key player in bone metabolism, Cathepsin K's dysregulation is a hallmark of osteoporosis, making compounds that can modulate its activity invaluable for therapeutic development.

Chemically, 2-Cyanopyrimidine is a white crystalline powder, typically supplied with high purity levels, often exceeding 99%. Its molecular formula, C5H3N3, and molecular weight of approximately 105.1 g/mol, define its structure as a pyrimidine derivative with a nitrile group. This specific chemical configuration is crucial for its biological activity. The compound's ability to act as a Cathepsin K inhibitor, with documented IC50 values, positions it as a critical building block in the pharmaceutical pipeline for anti-osteoporosis drugs. Researchers frequently purchase this intermediate to conduct in-vitro studies, screen for efficacy, and explore structure-activity relationships.

The therapeutic potential of 2-Cyanopyrimidine lies in its ability to target Cathepsin K, an enzyme that, when overactive, leads to the excessive breakdown of bone tissue. By inhibiting this enzyme, researchers aim to restore the balance of bone resorption and formation, thereby preventing bone loss and reducing fracture risk. This makes 2-Cyanopyrimidine not just a chemical compound, but a vital component in the complex process of discovering and manufacturing new pharmaceuticals. Pharmaceutical companies and research institutions looking to advance their osteoporosis drug development programs often seek reliable manufacturers and suppliers of such high-quality intermediates.

As a leading chemical supplier, we understand the importance of providing precisely specified compounds. When you buy 2-Cyanopyrimidine from us, you are acquiring a product that has undergone rigorous quality control, ensuring it meets the stringent requirements for pharmaceutical research. We offer competitive pricing and flexible purchasing options, making it easier for our clients to secure the materials they need. For any inquiries regarding the purchase or supply of 2-Cyanopyrimidine, our team is ready to assist, ensuring you have the necessary chemical building blocks to drive your osteoporosis therapy research forward.