Understanding how cells generate and utilize energy is fundamental to advancing research in numerous biological and medical fields. 2-Deoxy-D-glucose (2-DG), a glucose analog with the CAS number 154-17-6, plays a pivotal role in these investigations by specifically targeting and inhibiting glycolysis. As a specialized chemical supplier, we provide high-quality 2-DG to researchers worldwide, enabling critical studies into cellular energy dynamics.

The core mechanism of 2-DG lies in its ability to disrupt the glycolytic pathway, the primary route for ATP production in many cells. When 2-DG enters a cell, it is phosphorylated by hexokinase, forming 2-deoxy-D-glucose-6-phosphate. However, unlike glucose-6-phosphate, this metabolite cannot proceed through glycolysis due to the absence of the hydroxyl group at the second carbon. This 'metabolic trapping' leads to a depletion of cellular ATP and can also inhibit other enzymes in the pathway, thereby providing researchers with a direct method to probe the consequences of glycolytic inhibition.

This fundamental action makes 2-DG an essential chemical for a variety of research applications. In cancer research, it helps elucidate how altered glucose metabolism supports tumor growth and survival, and it is explored as a potential therapeutic agent to exploit these dependencies. Similarly, in studies of infectious diseases, understanding how viruses rely on host cell glycolysis is key to developing antiviral strategies, and 2-DG serves as a critical research tool in this area. Many scientists choose to buy 2-DG to investigate cellular stress responses, apoptosis, and the regulation of energy production.

The purity and consistency of 2-DG are paramount for obtaining accurate and reproducible results. As a dedicated manufacturer and supplier, we ensure that our 2-deoxy-D-glucose meets high purity standards (typically u226597% or u226598%), providing researchers with a reliable chemical for their experimental needs. We understand the diverse requirements of scientific inquiry and strive to offer this vital compound at competitive prices, coupled with comprehensive technical support.

For institutions and laboratories seeking to purchase 2-deoxy-D-glucose for their research into cellular energy metabolism, we offer a dependable supply chain. Our commitment as a China-based manufacturer ensures that you can procure this essential chemical intermediate with confidence, supporting your efforts to unravel complex biological processes and develop innovative therapeutic solutions.