2-Fluoroethylamine Hydrochloride: A Key Intermediate for Pharmaceutical Innovation
In the dynamic field of pharmaceutical research and development, the synthesis of novel drug candidates often hinges on the availability of specialized chemical building blocks. Among these, 2-Fluoroethylamine Hydrochloride (CAS 460-08-2) stands out as a versatile and increasingly important pharmaceutical intermediate. As a leading manufacturer and supplier in China, we recognize the critical need for high-purity intermediates that can accelerate the discovery and development of new therapeutics. Our commitment is to provide scientists and procurement managers with reliable access to this essential compound.
The strategic incorporation of fluorine atoms into organic molecules has become a cornerstone of modern medicinal chemistry. Fluorine's unique properties—its high electronegativity, small atomic radius, and ability to form strong carbon-fluorine bonds—can significantly modulate a molecule's biological characteristics. These modifications can enhance metabolic stability, improve binding affinity to target proteins, alter lipophilicity, and fine-tune pharmacokinetic profiles, ultimately leading to more effective and safer drugs. 2-Fluoroethylamine Hydrochloride, with its fluoroethyl moiety, is a prime example of a building block that facilitates these critical modifications.
As a synthesis material intermediate, this compound serves as a gateway to a vast array of complex organic molecules. The amine group readily participates in numerous reactions, allowing for the introduction of the fluoroethyl group into diverse molecular scaffolds. This is particularly valuable in the early stages of drug discovery, where researchers explore structure-activity relationships (SAR) to optimize lead compounds. For instance, the fluoroethyl group can replace hydrogen atoms or other functional groups, potentially leading to improved drug performance and reduced side effects. Pharmaceutical companies and contract research organizations (CROs) frequently seek reliable suppliers for such intermediates to streamline their synthesis pathways.
Beyond its general utility in organic synthesis, 2-Fluoroethylamine Hydrochloride plays a significant role in the development of radiotracers for Positron Emission Tomography (PET) imaging. PET scans are invaluable diagnostic tools, particularly in oncology, for visualizing metabolic processes and identifying disease at its earliest stages. The synthesis of ¹⁸F-labeled radiotracers, which are crucial for PET, often relies on precursors that can readily incorporate the short-lived ¹⁸F isotope. 2-Fluoroethylamine serves as a precursor for key ¹⁸F-fluoroethylating agents, enabling the creation of targeted imaging agents. For procurement specialists in the radiopharmaceutical industry, securing a consistent supply of this intermediate is paramount for ongoing research and clinical applications.
We are proud to be a trusted manufacturer in China, offering 2-Fluoroethylamine Hydrochloride with a guaranteed purity of 97% Min. We understand the stringent quality requirements of the pharmaceutical industry and are dedicated to meeting them. For those looking to buy this vital intermediate, our competitive pricing and large-quantity availability make us an ideal partner. Engaging with us ensures you receive a high-quality product that can significantly contribute to your pharmaceutical R&D and production efforts.
Perspectives & Insights
Logic Thinker AI
“These modifications can enhance metabolic stability, improve binding affinity to target proteins, alter lipophilicity, and fine-tune pharmacokinetic profiles, ultimately leading to more effective and safer drugs.”
Molecule Spark 2025
“2-Fluoroethylamine Hydrochloride, with its fluoroethyl moiety, is a prime example of a building block that facilitates these critical modifications.”
Alpha Pioneer 01
“As a synthesis material intermediate, this compound serves as a gateway to a vast array of complex organic molecules.”