The relentless pursuit of novel therapeutics in the pharmaceutical industry relies heavily on the availability of high-quality, specialized chemical intermediates. Among these, 2-Hydroxy-3-trifluoromethylpyridine (CAS 22245-83-6) stands out as a critical building block, indispensable for the synthesis of various bioactive molecules and drug candidates. For research scientists and pharmaceutical manufacturers, understanding the applications and reliable sourcing of this compound is paramount to driving innovation forward.

The structure of 2-Hydroxy-3-trifluoromethylpyridine, a trifluoromethyl-substituted 2-hydroxypyridine, provides a unique scaffold with inherent chemical properties that are highly valuable in medicinal chemistry. Its most notable application is as a reactant in the synthesis of Pyrido[2,3-b]pyrazine, a class of compounds that have shown significant promise as TRPV1 antagonists. TRPV1 antagonists are a target for managing pain and inflammation, highlighting the direct impact this intermediate can have on developing new treatment options.

Beyond this specific application, the broader 2-pyridone structure, often modified with functional groups like trifluoromethyl, is a common motif in many biologically active molecules. Research has explored imidazoline derivatives containing the 2-pyridone core as potent inhibitors of neuropeptide-Y receptor Y5, which could lead to treatments for obesity. This versatility makes 3-(Trifluoromethyl)pyridin-2-ol a highly sought-after compound for drug discovery programs aiming to identify new therapeutic agents. Procurement specialists looking to buy this intermediate are essentially investing in the potential for groundbreaking pharmaceutical development.

As a supplier of essential pharmaceutical intermediates, we recognize the stringent quality requirements of this sector. Our commitment is to provide 2-Hydroxy-3-trifluoromethylpyridine at high purity levels, ensuring that it meets the exacting standards necessary for drug synthesis. When you partner with us, you gain access to a reliable source of this vital chemical, facilitating smoother R&D processes and potential scale-up for manufacturing. Inquiring about bulk pricing and sample availability is the first step towards integrating this valuable building block into your product development pipeline.

In conclusion, 2-Hydroxy-3-trifluoromethylpyridine is a cornerstone intermediate for pharmaceutical innovation. Its role in creating potential new drugs for conditions like pain and obesity underscores its importance. For pharmaceutical companies and research institutions looking to purchase high-quality 3-(Trifluoromethyl)pyridin-2-one, partnering with a reputable manufacturer and supplier is key. We invite you to reach out to us for detailed product information, competitive quotes, and to secure a dependable supply of this crucial building block for your pharmaceutical research and manufacturing needs.