For professionals in the chemical and pharmaceutical industries, understanding the precise specifications and purity requirements of raw materials is fundamental to successful product development and manufacturing. 2-Hydroxyquinoline-4-carboxylic acid, also commonly known as 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 15733-89-8), is one such compound where meticulous attention to quality is paramount. Whether you are a procurement manager looking to buy or an R&D scientist specifying materials, this guide outlines the essential purity standards and specification details for this vital intermediate.

The Importance of Purity in Chemical Intermediates

Chemical intermediates are the foundation upon which more complex molecules, such as Active Pharmaceutical Ingredients (APIs) or high-performance cosmetic ingredients, are built. The purity of these intermediates directly influences the efficacy, safety, and stability of the final product. Impurities, even in trace amounts, can lead to unwanted side reactions, reduced yields, or the formation of toxic byproducts. Consequently, buyers frequently search for terms like 'high purity 2-hydroxyquinoline-4-carboxylic acid' or 'CAS 15733-89-8 specification sheet' to ensure they are sourcing materials that meet stringent quality benchmarks.

Key Specification Parameters for 15733-89-8

When procuring 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid, several key parameters are consistently specified by reputable manufacturers and sought after by buyers:

  1. Purity Level: The most critical specification is the purity, commonly stated as ≥98% or even ≥99% when analyzed by techniques such as High-Performance Liquid Chromatography (HPLC). This guarantees that the bulk of the material consists of the target compound.
  2. Appearance: The typical appearance for this compound is a white or off-white powder. Deviations from this can indicate potential contamination or degradation.
  3. Molecular Formula and Weight: The molecular formula is C10H7NO3, with a molecular weight of 189.17 g/mol. These are fundamental identifiers for the compound.
  4. Solubility: Information on solubility in common solvents is often provided, which is crucial for planning reaction conditions and formulation processes.
  5. Melting Point: While not always provided, a melting point range can serve as an indicator of purity. For 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid, it is often reported as >300 °C or around 350 °C.
  6. CAS Number: The Chemical Abstracts Service (CAS) Registry Number, 15733-89-8, is a unique identifier crucial for unambiguous identification in global trade and research.

Sourcing with Confidence: Manufacturer and Supplier Roles

Reputable manufacturers and suppliers of 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid will provide comprehensive documentation, including Certificates of Analysis (CoA) for each batch, detailing these specifications and the analytical methods used. When you buy from a trusted manufacturer, you gain assurance that these standards are rigorously maintained throughout the production process. If you are looking to buy from a supplier, particularly in China, verify their capacity to meet these purity requirements and their commitment to quality control.

Conclusion

For any application requiring 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid, adhering to strict purity standards is non-negotiable. By carefully reviewing specifications, demanding accurate documentation from suppliers, and prioritizing manufacturers with robust quality assurance systems, buyers can ensure they are obtaining a high-quality intermediate that will contribute to the success of their critical projects.