In the intricate world of pharmaceutical development, the selection and sourcing of high-quality chemical intermediates play a pivotal role in the success of drug synthesis. Among these crucial building blocks is 2-Indanone (CAS 615-13-4), a versatile compound widely recognized for its importance in creating active pharmaceutical ingredients (APIs). This article delves into the properties and applications of 2-Indanone, highlighting why it is an indispensable intermediate for manufacturers and researchers alike.

Understanding the Chemistry of 2-Indanone

2-Indanone, chemically known as Indan-2-one, is characterized by a bicyclic structure fusing a benzene ring with a cyclopentanone ring. Its molecular formula is C9H8O, with a molecular weight of 132.16 g/mol. Typically, it presents as a solid, often appearing as needle-shaped crystals or a crystalline powder, ranging from colorless to pale yellow or light brown. Key physical properties include a melting point between 51-54°C and a boiling point of 218°C. While sparingly soluble in water, it dissolves readily in common organic solvents like chloroform and ethyl acetate, facilitating its use in various reaction media. Its moderate odor is described as tenacious. These properties make it a convenient and effective reagent for synthetic chemists.

The Crucial Role of 2-Indanone in Pharmaceutical Synthesis

The primary application of 2-Indanone lies in its function as a vital intermediate for the synthesis of numerous pharmaceutical compounds. It is particularly noted for its role in the preparation of:

  • Aprindine Hydrochloride: An antiarrhythmic agent used to treat cardiac arrhythmias. 2-Indanone serves as a key precursor in its multi-step synthesis.
  • Ceforanide: A second-generation cephalosporin antibiotic used to treat bacterial infections. The synthesis of this potent antibiotic relies on 2-Indanone as a foundational intermediate.

Beyond these established uses, 2-Indanone derivatives are continuously being explored for their potential therapeutic activities, including anti-inflammatory and anticancer properties. This ongoing research underscores the compound's versatility and its continued importance in the discovery of new medicines.

Why Choose a Reliable Supplier for 2-Indanone?

For businesses involved in pharmaceutical manufacturing, securing a consistent and high-quality supply of intermediates like 2-Indanone is critical. NINGBO INNO PHARMCHEM CO.,LTD., a leading 2-Indanone manufacturer in China, understands these demands. We ensure our 2-Indanone meets stringent purity requirements, essential for the efficacy and safety of the final drug products. By choosing us as your 2-Indanone supplier, you benefit from our robust manufacturing processes, competitive pricing, and commitment to reliable delivery, ensuring your R&D and production pipelines remain uninterrupted.

Whether you are researching new therapeutic agents or scaling up existing drug production, having a dependable source for intermediates like 2-Indanone is paramount. We invite you to contact us to learn more about our high-purity 2-Indanone and how we can support your pharmaceutical synthesis needs.