In the intricate world of chemical manufacturing, specific intermediates play pivotal roles in enabling the creation of complex and valuable compounds. 2'-Iodoacetophenone (CAS 2142-70-3) is one such critical intermediate, distinguished by its unique chemical structure and reactivity, which make it indispensable in various industrial applications, particularly in pharmaceuticals and material science. As a trusted manufacturer and supplier, we are pleased to provide comprehensive insights into this important chemical.

Understanding the Properties of 2'-Iodoacetophenone

2'-Iodoacetophenone, with the molecular formula C8H7IO and a molecular weight of approximately 246.05 g/mol, typically presents as a yellow to amber solid or liquid. Its physical state can vary depending on temperature, with a reported melting point in the range of 29-32°C. The compound exhibits a density of around 1.78 g/cm³ and a refractive index of 1.618. It is soluble in common organic solvents like ethanol and ether but is practically insoluble in water. This solubility profile is characteristic of many organic intermediates and is a key consideration during reaction work-ups and purification processes.

Chemically, the presence of the iodine atom, a good leaving group, and the carbonyl functionality renders 2'-Iodoacetophenone highly reactive. It readily participates in nucleophilic substitution reactions and can be modified through various synthetic routes. These properties make it a versatile building block for creating more complex organic molecules.

Synthesis and Manufacturing Excellence

The synthesis of 2'-Iodoacetophenone can be achieved through several chemical pathways. A common method involves the iodination of acetophenone derivatives, often employing catalysts and specific reaction conditions to ensure regioselectivity and high yields. Our manufacturing process is optimized for efficiency and purity, ensuring that we can supply 2'-Iodoacetophenone that consistently meets stringent quality requirements. As a leading supplier from China, we pride ourselves on our advanced production technologies and robust quality control systems.

Industrial Applications: From Pharmaceuticals to Materials

The primary utility of 2'-Iodoacetophenone lies in its role as an intermediate:

  • Pharmaceutical Intermediates: It is a crucial component in the synthesis of numerous pharmaceutical drugs and active pharmaceutical ingredients (APIs). Its structure can be elaborated to create a wide range of therapeutic agents.
  • Material Science: Researchers utilize 2'-Iodoacetophenone in the development of novel materials, including polymers with tailored electronic or optical properties, contributing to advancements in fields like organic electronics and photonics.
  • Fine Chemical Production: It serves as a building block for various fine chemicals, contributing to the fragrance industry and the synthesis of other specialized organic compounds.

For those looking to buy 2'-Iodoacetophenone, partnering with a reliable manufacturer like ourselves ensures access to a high-quality product at competitive prices. We are dedicated to supporting your chemical synthesis needs with our expertise and comprehensive supply chain solutions.