The pharmaceutical industry relies heavily on a diverse palette of chemical intermediates to synthesize novel drug candidates and optimize existing therapies. Among these, 2-Iodophenylacetic Acid (CAS: 18698-96-9) has carved out a significant niche due to its unique structural features that lend themselves to complex synthetic transformations. As a specialized manufacturer, we understand its importance in pharmaceutical R&D and are committed to providing a consistent, high-purity supply.

The Chemical Backbone for Drug Development

2-Iodophenylacetic Acid, with its molecular formula C8H7IO2, is a phenylacetic acid derivative featuring an iodine atom strategically placed on the aromatic ring. This halogen substituent acts as a versatile handle for various chemical reactions, making it an ideal building block in drug synthesis. Its primary utility lies in its ability to participate in metal-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings. These reactions are fundamental for constructing carbon-carbon and carbon-heteroatom bonds, which are crucial for assembling the complex molecular scaffolds of many modern pharmaceuticals. When pharmaceutical companies need to buy 2-Iodophenylacetic Acid, they are seeking a reliable source that guarantees the high purity (typically 97%+) required for their sensitive synthetic processes.

Applications in Medicinal Chemistry

Medicinal chemists utilize 2-Iodophenylacetic Acid to introduce specific structural motifs or to act as a precursor for a wide range of biologically active molecules. Its carboxylic acid functionality can be easily converted into esters or amides, further enhancing its synthetic flexibility. The ortho-iodine atom allows for regioselective functionalization of the phenyl ring, which is often a key step in optimizing a drug candidate’s pharmacokinetic and pharmacodynamic properties. For those engaged in drug discovery, inquiring about the price and availability from experienced chemical suppliers is a crucial step in project planning.

Ensuring Quality and Supply for R&D

The rigorous demands of pharmaceutical research and development necessitate intermediates that are not only pure but also consistently available. Our company, as a dedicated manufacturer, focuses on stringent quality control to ensure that every batch of 2-Iodophenylacetic Acid meets the exacting standards of the industry. We understand that reliable supply is as critical as product quality. Therefore, we encourage R&D professionals to engage with us early in their project lifecycle to discuss their sourcing needs. Obtaining a free sample allows for initial validation, paving the way for larger orders as projects progress.

As the pharmaceutical landscape continues to evolve, intermediates like 2-Iodophenylacetic Acid remain indispensable tools for innovation. We are proud to support this vital sector by providing a high-quality, reliably sourced chemical building block.