2-Methyl-D-phenylalanine: A Versatile Chiral Building Block for Pharmaceutical Innovation
The pharmaceutical industry relies heavily on precise molecular engineering to develop effective and safe therapeutics. Chiral building blocks, which possess non-superimposable mirror images, are fundamental to this process, especially in creating enantiomerically pure active pharmaceutical ingredients (APIs). 2-Methyl-D-phenylalanine (CAS: 80126-54-1) stands out as a valuable chiral intermediate, offering unique opportunities for pharmaceutical innovation.
The Importance of Chirality in Pharmaceuticals
Enantiomers of a drug molecule can exhibit vastly different pharmacological activities, potencies, and even toxicities. Therefore, the ability to synthesize compounds with a specific chirality is critical. 2-Methyl-D-phenylalanine, with its defined D-configuration and a chiral center, provides a stereochemically pure starting point for constructing complex drug molecules. Its structure, featuring a methyl group on the phenyl ring, further differentiates it from standard phenylalanine derivatives.
Applications in Pharmaceutical R&D
As a versatile building block, 2-Methyl-D-phenylalanine can be utilized in several ways:
- API Synthesis: It serves as a key intermediate in the synthesis of various APIs where a modified phenylalanine moiety is required.
- Drug Discovery: Researchers can incorporate it into lead compounds to explore structure-activity relationships (SAR) and optimize drug properties like target binding and metabolic stability.
- Peptidomimetics: Its incorporation into peptidomimetic structures can lead to compounds with improved oral bioavailability and resistance to enzymatic cleavage.
Reliable Sourcing from Global Manufacturers
Procuring high-quality 2-Methyl-D-phenylalanine is essential for the success of pharmaceutical R&D projects. We act as a bridge, connecting you with reliable manufacturers and suppliers of this specialty chemical. When you buy 2-Methyl-D-phenylalanine from us, you are assured of product integrity and consistent availability, enabling your research and development efforts to proceed without interruption. Our network of suppliers, particularly in China, offers competitive pricing and a robust supply chain for this crucial pharmaceutical intermediate.
For companies seeking to push the boundaries of pharmaceutical innovation, access to sophisticated chiral building blocks like 2-Methyl-D-phenylalanine is indispensable. We are dedicated to facilitating this access, providing researchers and procurement specialists with the high-quality materials they need to bring life-changing medicines to market.
Perspectives & Insights
Molecule Vision 7
“The Importance of Chirality in PharmaceuticalsEnantiomers of a drug molecule can exhibit vastly different pharmacological activities, potencies, and even toxicities.”
Alpha Origin 24
“Therefore, the ability to synthesize compounds with a specific chirality is critical.”
Future Analyst X
“2-Methyl-D-phenylalanine, with its defined D-configuration and a chiral center, provides a stereochemically pure starting point for constructing complex drug molecules.”