The world of organic chemistry is built upon a foundation of reliable and well-characterized intermediates. Among these, heterocyclic compounds like 2-Phenylthiophene (CAS 825-55-8) play a vital role in the development of complex molecules, particularly within the pharmaceutical and fine chemical industries. Understanding its properties and applications is essential for researchers and procurement specialists alike.

Understanding 2-Phenylthiophene: Properties and Characteristics

2-Phenylthiophene is an organic compound characterized by a phenyl group attached to the second position of a thiophene ring. Its chemical formula is C10H8S, and it has a molecular weight of approximately 160.24 g/mol. Key physical properties include:

  • Appearance: Typically appears as a light brown solid or crystalline powder.
  • Melting Point: Ranges from 34-36 °C, indicating it is a low-melting solid at room temperature.
  • Boiling Point: Approximately 254-256 °C at atmospheric pressure.
  • Purity: Commonly available at high purity levels, often 97% min, which is critical for its use in sensitive synthetic applications.

These characteristics make 2-Phenylthiophene a stable and manageable compound for laboratory and industrial use. Its structure provides multiple sites for further chemical modification, making it an attractive building block.

Applications in Synthesis

The primary application of 2-Phenylthiophene is as a key intermediate in the synthesis of more complex organic molecules. Its utility spans several areas:

  • Pharmaceutical Intermediates: It serves as a crucial precursor in the multi-step synthesis of various pharmaceutical compounds. The thiophene moiety is present in numerous drugs due to its favorable biological activity and pharmacokinetic properties.
  • Organic Synthesis: Researchers utilize it in a wide range of organic transformations, including cross-coupling reactions, functionalization, and the construction of heterocyclic systems.
  • Material Science: While less common, thiophene derivatives can also find applications in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) or conductive polymers, due to their conjugated pi systems.

Sourcing Strategy for 2-Phenylthiophene

When procurement professionals need to buy 2-Phenylthiophene (CAS 825-55-8), partnering with reputable chemical suppliers is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted manufacturer and supplier that offers high-purity 2-Phenylthiophene. Sourcing directly from manufacturers can ensure competitive pricing, consistent quality, and reliable supply, which are all critical factors for successful R&D and production. When making your purchase, always request a Certificate of Analysis (COA) to verify the product's specifications.

In summary, 2-Phenylthiophene is a fundamental building block with significant utility in organic and pharmaceutical synthesis. Its consistent availability in high purity from reliable suppliers is essential for advancing chemical innovation.