20-(tert-Butoxy)-20-oxoicosanoic Acid: A Key Linker in Antibody-Drug Conjugate (ADC) Development
Antibody-Drug Conjugates (ADCs) have revolutionized cancer therapy by enabling the targeted delivery of potent cytotoxic drugs directly to cancer cells, minimizing damage to healthy tissues. The efficacy of an ADC hinges on several components, including the antibody, the payload (drug), and crucially, the linker that connects them. 20-(tert-Butoxy)-20-oxoicosanoic acid (CAS: 683239-16-9) has gained prominence as a valuable intermediate in the synthesis of these sophisticated linkers.
As a chemical intermediate, 20-(tert-Butoxy)-20-oxoicosanoic acid offers a robust aliphatic chain that can be functionalized to create stable, non-cleavable linkers. These types of linkers are essential for ensuring that the drug remains attached to the antibody until it reaches the target cancer cell, thereby maximizing therapeutic effect and reducing systemic toxicity. The specific chemical structure of this compound facilitates its integration into complex linker architectures, contributing to the overall stability and pharmacokinetic properties of the ADC.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying researchers and manufacturers with high-purity 20-(tert-Butoxy)-20-oxoicosanoic acid to support the advancement of ADC technology. Our role as a dependable supplier in China ensures that the critical building blocks for these life-saving therapies are readily available. By providing access to this vital pharmaceutical intermediate, we empower scientists to develop more effective and safer cancer treatments. The precise control over molecular structure offered by this intermediate is key to designing ADCs with improved therapeutic indices.
The ongoing progress in ADC development continues to highlight the importance of specialized chemical intermediates. The ability to reliably synthesize ADCs with specific linker chemistries, often utilizing compounds like 20-(tert-Butoxy)-20-oxoicosanoic acid, is fundamental to the success of precision medicine. Our dedication to quality and consistent supply ensures that the field of targeted cancer therapy can continue to innovate and offer hope to patients worldwide.
As a chemical intermediate, 20-(tert-Butoxy)-20-oxoicosanoic acid offers a robust aliphatic chain that can be functionalized to create stable, non-cleavable linkers. These types of linkers are essential for ensuring that the drug remains attached to the antibody until it reaches the target cancer cell, thereby maximizing therapeutic effect and reducing systemic toxicity. The specific chemical structure of this compound facilitates its integration into complex linker architectures, contributing to the overall stability and pharmacokinetic properties of the ADC.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying researchers and manufacturers with high-purity 20-(tert-Butoxy)-20-oxoicosanoic acid to support the advancement of ADC technology. Our role as a dependable supplier in China ensures that the critical building blocks for these life-saving therapies are readily available. By providing access to this vital pharmaceutical intermediate, we empower scientists to develop more effective and safer cancer treatments. The precise control over molecular structure offered by this intermediate is key to designing ADCs with improved therapeutic indices.
The ongoing progress in ADC development continues to highlight the importance of specialized chemical intermediates. The ability to reliably synthesize ADCs with specific linker chemistries, often utilizing compounds like 20-(tert-Butoxy)-20-oxoicosanoic acid, is fundamental to the success of precision medicine. Our dedication to quality and consistent supply ensures that the field of targeted cancer therapy can continue to innovate and offer hope to patients worldwide.
Perspectives & Insights
Data Seeker X
“These types of linkers are essential for ensuring that the drug remains attached to the antibody until it reaches the target cancer cell, thereby maximizing therapeutic effect and reducing systemic toxicity.”
Chem Reader AI
“The specific chemical structure of this compound facilitates its integration into complex linker architectures, contributing to the overall stability and pharmacokinetic properties of the ADC.”
Agile Vision 2025
“is committed to supplying researchers and manufacturers with high-purity 20-(tert-Butoxy)-20-oxoicosanoic acid to support the advancement of ADC technology.”