In the dynamic field of pharmaceutical development and organic synthesis, the selection of high-quality chemical building blocks is paramount. 3,5-Dichloro-2,6-dimethoxybenzoic acid (CAS: 73219-91-7) stands out as a particularly versatile and essential intermediate. This article explores its significance, applications, and provides guidance for procurement professionals and researchers looking to source this compound reliably.

The Chemistry Behind the Intermediate

3,5-Dichloro-2,6-dimethoxybenzoic acid is a functionalized aromatic carboxylic acid. Its structure is characterized by a benzoic acid ring bearing two chlorine atoms at the 3 and 5 positions, and two methoxy groups at the 2 and 6 positions. This specific arrangement of substituents imbues the molecule with distinct reactivity and solubility properties, making it valuable in multistep organic syntheses. Manufacturers typically supply this compound with a minimum purity of 97%, often appearing as a white to off-white crystalline powder. Its melting point, falling between 99-101°C, is a key specification for quality verification.

Key Applications in Modern Synthesis

The utility of 3,5-Dichloro-2,6-dimethoxybenzoic acid spans several areas within chemical research and pharmaceutical manufacturing:

  1. Pharmaceutical Intermediates: Its most prominent role is as an intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Specifically, it's utilized in the creation of dopamine D2 receptor antagonists, compounds critical for treating neurological disorders such as schizophrenia and Parkinson's disease.
  2. Organic Synthesis Building Block: Beyond its pharmaceutical applications, the compound serves as a versatile building block for creating a wide array of complex organic molecules used in agrochemicals, materials science, and specialized research chemicals.
  3. Research and Development: For academic and industrial research laboratories, having access to high-purity 3,5-Dichloro-2,6-dimethoxybenzoic acid is essential for exploring new synthetic pathways and developing novel compounds.

Procurement: Ensuring Quality and Reliability

When you need to buy 3,5-Dichloro-2,6-dimethoxybenzoic acid, partnering with a reputable supplier is key. As a manufacturer and supplier based in China, we understand the importance of consistency and quality. We recommend looking for suppliers who:

  • Clearly state product specifications, including purity and CAS number (73219-91-7).
  • Provide Certificates of Analysis (CoA) with each batch.
  • Offer competitive pricing for both R&D quantities and bulk orders.
  • Ensure proper packaging and shipping conditions (e.g., sealed, dry, 2-8°C storage).
  • Have responsive customer support and technical assistance.

Engaging with a supplier that offers a free sample can provide an excellent opportunity to evaluate product quality firsthand before placing a larger order. The competitive market for chemical intermediates means that obtaining a quote and comparing offerings from different manufacturers can lead to significant cost savings without compromising on quality.

In conclusion, 3,5-Dichloro-2,6-dimethoxybenzoic acid is an indispensable intermediate for many cutting-edge scientific and pharmaceutical applications. By prioritizing quality and reliable sourcing from experienced manufacturers and suppliers, researchers and procurement professionals can ensure the success of their vital projects.