3,5-Dimethylpyrazole: Properties, Applications, and Chemical Synthesis Insights
3,5-Dimethylpyrazole (CAS 67-51-6) is a fundamental heterocyclic compound that plays a significant role in various chemical industries. Its well-defined properties and versatile reactivity make it an indispensable intermediate for a wide range of synthetic processes. Understanding its characteristics and applications is crucial for chemists, researchers, and procurement professionals.
Physically, 3,5-Dimethylpyrazole typically presents as a white crystalline powder, with a melting point in the range of 105-108°C. Its molecular formula is C5H8N2, and its molecular weight is approximately 96.13 g/mol. The compound is stable under normal storage conditions and is soluble in various organic solvents, though sparingly soluble in water.
The applications of 3,5-Dimethylpyrazole are notably diverse:
- Organic Synthesis: It serves as a crucial building block and intermediate for the synthesis of complex organic molecules, including dyestuffs, photochemicals, and agrochemicals.
- Polyurethane Systems: It functions as an effective isocyanate blocking agent, forming stable one-component formulations and allowing controlled curing at elevated temperatures. This is particularly relevant for coatings and adhesives.
- Nitrification Inhibition: In agriculture, it is used as a nitrification inhibitor in fertilizers, enhancing nitrogen use efficiency and reducing environmental losses.
- Pharmaceuticals: It is a vital intermediate in the synthesis of various pharmaceutical compounds and APIs, contributing to drug development and manufacturing.
The synthesis of 3,5-Dimethylpyrazole is commonly achieved through the reaction of pentane-2,4-dione with hydrazine hydrate. This reaction is straightforward and can be carried out under various conditions, yielding the desired product with high efficiency. Manufacturers often optimize these processes to achieve the high purity levels (≥99.0%) required for demanding applications.
For businesses seeking to procure 3,5-Dimethylpyrazole, partnering with reputable suppliers and manufacturers, particularly those based in China, can offer significant advantages in terms of quality, price, and supply chain reliability. Access to detailed specifications, COAs, and MSDS is essential for informed purchasing decisions. By leveraging the expertise of these suppliers, industries can ensure they are utilizing a high-quality intermediate for their critical chemical processes.
Perspectives & Insights
Logic Thinker AI
“The synthesis of 3,5-Dimethylpyrazole is commonly achieved through the reaction of pentane-2,4-dione with hydrazine hydrate.”
Molecule Spark 2025
“This reaction is straightforward and can be carried out under various conditions, yielding the desired product with high efficiency.”
Alpha Pioneer 01
“Manufacturers often optimize these processes to achieve the high purity levels (≥99.”