The landscape of pharmaceutical development is continuously evolving, driven by the quest for novel therapeutics. At the heart of this innovation are chemical building blocks – versatile molecules that form the foundation for new drug candidates. Among these, 3-Amino-3-(2-bromophenyl)-propionic acid stands out due to its unique structural features, making it an invaluable asset for synthetic chemists and formulation scientists. Understanding its properties and how to effectively purchase it from reliable manufacturers is key for any research-driven pharmaceutical enterprise.

Chemical Profile and Significance

Characterized by its CAS number 117391-48-7 and appearance as a white to off-white solid or powder, 3-Amino-3-(2-bromophenyl)-propionic acid offers a potent combination of an amino acid moiety and a brominated aromatic ring. This dual functionality allows for a wide array of chemical transformations. The presence of bromine provides a handle for cross-coupling reactions, while the amino and carboxylic acid groups are ripe for peptide bond formation, esterification, and amidation. This versatility makes it a cornerstone for chemists looking to synthesize complex molecules with specific biological activities.

Applications in Drug Discovery and Development

The utility of 3-Amino-3-(2-bromophenyl)-propionic acid extends across various stages of pharmaceutical R&D:

  • API Synthesis: It serves as a crucial intermediate in the multi-step synthesis of APIs, where its specific structure contributes to the final drug's pharmacological profile.
  • Peptide Mimetics: As a non-natural amino acid derivative, it can be incorporated into peptide sequences to enhance stability, bioavailability, or receptor binding affinity.
  • Scaffold Development: The bromophenyl group can be a starting point for diversity-oriented synthesis, allowing for the rapid generation of compound libraries for high-throughput screening.
  • Medicinal Chemistry: Its functional groups are ideal for structure-activity relationship (SAR) studies, enabling medicinal chemists to fine-tune drug candidates.

For pharmaceutical companies aiming to buy advanced intermediates, securing a consistent supply of high-purity 3-Amino-3-(2-bromophenyl)-propionic acid is essential. Working with a dedicated supplier ensures that your R&D pipeline remains robust and that your manufacturing processes are supported by quality raw materials. Explore options from leading manufacturers who can guarantee the specifications you need.