The relentless pursuit of novel therapeutics in the pharmaceutical industry relies heavily on a diverse array of high-quality chemical intermediates. Among these, 3-Amino-3-(4-chlorophenyl)propionic Acid (CAS: 19947-39-8) stands out as a valuable chiral building block with significant potential in drug discovery and development. Understanding its utility and sourcing it effectively is crucial for R&D teams.

The Role of 3-Amino-3-(4-chlorophenyl)propionic Acid in Drug Discovery

As an amino acid derivative containing a chlorophenyl moiety, this compound offers unique structural features that medicinal chemists can leverage. Its chiral center allows for the synthesis of enantiomerically pure compounds, which is often critical for achieving desired pharmacological activity and minimizing off-target effects. Researchers utilize intermediates like 3-Amino-3-(4-chlorophenyl)propionic Acid to construct complex molecular scaffolds for potential drug candidates targeting a wide range of therapeutic areas.

Its incorporation into molecular structures can influence properties such as binding affinity to biological targets, metabolic stability, and pharmacokinetic profiles. The chlorophenyl group can also participate in specific interactions within the binding site of a protein, contributing to the efficacy of a drug candidate.

Procurement for Pharmaceutical R&D

For pharmaceutical research and development, the quality and reliability of chemical suppliers are paramount. Procurement managers often seek out manufacturers who can consistently supply 3-Amino-3-(4-chlorophenyl)propionic Acid with:

  • High Purity: Typically exceeding 97%, verified by robust analytical methods like HPLC and NMR.
  • Stereochemical Purity: If specific enantiomers are required, the supplier must confirm enantiomeric excess.
  • Consistent Batch Quality: Ensuring that each delivery meets the same high standards is vital for reproducible research outcomes.
  • Comprehensive Documentation: Certificates of Analysis (CoA) detailing purity, identification, and any relevant physical properties are indispensable.

As a dedicated supplier and manufacturer of specialty chemicals, we understand the stringent requirements of the pharmaceutical industry. We offer 3-Amino-3-(4-chlorophenyl)propionic Acid (CAS 19947-39-8) in high-purity grades, backed by thorough quality control and comprehensive documentation. We encourage R&D professionals to contact us to inquire about pricing and to obtain samples for their critical research projects.

Considerations for Synthesis and Formulation

When integrating 3-Amino-3-(4-chlorophenyl)propionic Acid into synthesis schemes, researchers should consider its reactivity and potential side reactions. Its functional groups – the amine and carboxylic acid – allow for a variety of derivatizations, including amide couplings, esterifications, and further modifications of the aromatic ring. Understanding these possibilities helps in designing efficient synthetic routes for novel drug molecules.

In conclusion, 3-Amino-3-(4-chlorophenyl)propionic Acid is an important intermediate for pharmaceutical R&D, offering a versatile platform for synthesizing new drug candidates. By partnering with reliable manufacturers who prioritize purity and consistency, pharmaceutical companies can accelerate their drug discovery pipelines.