In the fast-paced world of chemical research and development, identifying and securing reliable sources for crucial intermediates is a constant challenge. 3-Amino-3-phenylpropionic Acid (CAS 614-19-7) is one such compound, highly valued for its versatility as a building block in both pharmaceutical synthesis and advanced materials development. This white crystalline powder, often referred to as beta-phenylalanine, plays a significant role in creating complex molecules that drive innovation. For researchers and procurement specialists, understanding its synthesis, applications, and how to buy it effectively is essential.

Synthesis Pathways for 3-Amino-3-phenylpropionic Acid

The production of 3-Amino-3-phenylpropionic Acid typically involves several established organic synthesis routes. While specific proprietary methods may vary among manufacturers, common approaches often utilize starting materials such as phenylacetaldehyde or related derivatives. Key reactions might include amination followed by carbonylation or variations involving Strecker synthesis-type pathways adapted for beta-amino acids. The goal is to efficiently assemble the molecule with its characteristic phenyl, amino, and carboxyl groups on the beta-carbon. The resulting product is often obtained as a racemic mixture (DL-form), which is suitable for many industrial applications. For specific enantiopure requirements, further chiral resolution steps would be necessary, a process that manufacturers might offer.

Key Applications Driving Demand

The utility of 3-Amino-3-phenylpropionic Acid stems from its ability to serve as a critical intermediate. In the pharmaceutical sector, its applications are particularly noteworthy:

  • Platelet Aggregation Inhibitors: It is a vital precursor in the synthesis of compounds that help prevent blood clots, crucial for cardiovascular health.
  • Hormone Receptor Antagonists: It acts as a reagent in creating antagonists for human gonadotropin-releasing hormone (GnRH), used in treating various hormone-dependent conditions.

Beyond pharmaceuticals, its structure lends itself to material science. Researchers are exploring its use in creating novel biomaterials, functional polymers, and even as a component in nanomaterials due to its reactive functional groups and aromatic ring. This makes it a compound of interest for companies developing next-generation adhesives, coatings, and biocompatible materials.

Sourcing and Purchasing Considerations for R&D

For research and development purposes, obtaining 3-Amino-3-phenylpropionic Acid requires careful supplier selection. Researchers often need high-purity grades to ensure the integrity of experimental results. When you are looking to buy this compound, consider the following:

  • Purity Levels: Specify the required purity (e.g., 98% or 99% by HPLC) and verify it through the supplier's Certificate of Analysis (CoA).
  • Quantity: Ensure suppliers offer suitable quantities, from gram-scale for laboratory experiments to kilogram-scale for pilot studies.
  • Supplier Reputation: Choose manufacturers with a good reputation for quality control, reliable delivery, and responsive customer service. Many established chemical companies in China are excellent sources for this intermediate.
  • Pricing: While research quantities might have fixed prices, inquiring about bulk discounts for larger R&D projects or future manufacturing needs can be beneficial.

When you purchase from a reputable chemical manufacturer, you gain access to a crucial building block that can accelerate your research and development efforts. Understanding the synthesis and applications empowers you to articulate your needs precisely, ensuring you receive a product that meets your demanding standards. Whether for drug discovery or material innovation, 3-Amino-3-phenylpropionic Acid is a valuable chemical intermediate.