In the intricate world of pharmaceutical development, the quality and availability of chemical intermediates are foundational. 3-Bromo-5-methylisoxazole, identified by its CAS number 25741-97-3, stands out as a pivotal heterocyclic building block for the synthesis of Active Pharmaceutical Ingredients (APIs). For pharmaceutical researchers and procurement specialists, understanding the value and sourcing options for this compound is essential.

The Chemical Profile of 3-Bromo-5-methylisoxazole

With the molecular formula C4H4BrNO and a molecular weight of 161.98 g/mol, 3-bromo-5-methylisoxazole offers a specific reactivity profile that makes it highly sought after. Its structure, featuring a bromine atom on the isoxazole ring, facilitates a variety of chemical reactions crucial for complex API synthesis. Key parameters such as a boiling point of 202.1°C and a flash point of 76°C are important considerations for handling and storage. The requirement for high purity, often exceeding 97%, underscores its application in sensitive pharmaceutical processes.

Driving API Innovation

The versatility of 3-bromo-5-methylisoxazole as a synthetic intermediate allows for its incorporation into numerous drug candidate structures. Its ability to undergo reactions like Suzuki-Miyaura coupling, Buchwald-Hartwig amination, and other C-C or C-N bond formations makes it a cornerstone for medicinal chemists designing novel therapeutic agents. Sourcing this compound reliably is key to maintaining the momentum of drug discovery and development pipelines.

Strategic Sourcing from China

For businesses seeking to buy 3-bromo-5-methylisoxazole, China presents a significant advantage in terms of both cost-effectiveness and production scale. Leading chemical manufacturers and suppliers in China are equipped with advanced synthesis capabilities and stringent quality control measures to deliver high-purity intermediates consistently. When you inquire about purchasing CAS 25741-97-3 from a reputable Chinese manufacturer, you can expect competitive pricing, especially for bulk orders. Furthermore, these suppliers are experienced in global logistics, ensuring timely delivery to research institutions and manufacturing sites worldwide.

Ensuring Quality and Reliability for Your Projects

Procurement managers and R&D scientists must prioritize suppliers who can guarantee the specifications of 3-bromo-5-methylisoxazole. This includes providing detailed Certificates of Analysis (CoA) and ensuring batch-to-batch consistency. Engaging with manufacturers who offer customized synthesis services can also be beneficial for projects requiring specific derivatives or quantities. By selecting a dependable supplier, you mitigate risks associated with inconsistent quality or supply chain disruptions, thereby safeguarding your project timelines and the integrity of your final pharmaceutical products.

In summary, 3-bromo-5-methylisoxazole (CAS 25741-97-3) is an indispensable intermediate for pharmaceutical innovation. By leveraging the expertise and manufacturing capabilities of Chinese suppliers, companies can secure high-quality, cost-effective sourcing, thereby accelerating the path from laboratory discovery to life-saving medicines.