Fine chemicals are the backbone of many advanced industries, providing the precise molecular structures necessary for cutting-edge products. Among these, 3-Bromothiophene (CAS 872-31-1) stands out as a highly versatile and important intermediate, valued for its specific chemical properties and broad applicability in organic synthesis.

Understanding 3-Bromothiophene: Properties and Significance

3-Bromothiophene is an organobromine compound with the molecular formula C4H3BrS and a molecular weight of 163.03. Its physical characteristics include being a clear to pale yellow liquid, with a boiling point of 158.4 °C. The significance of 3-Bromothiophene lies in its dual functionality: the thiophene ring provides a unique aromatic system, while the bromine atom at the 3-position offers a reactive site for a multitude of chemical transformations.

This makes it an ideal starting material or intermediate for synthesizing a wide range of complex organic molecules. Its primary utility is found in:

  • Organic Synthesis: It’s a key reactant in various cross-coupling reactions, facilitating the formation of new carbon-carbon bonds. This is fundamental for building intricate molecular architectures.
  • Pharmaceutical Intermediates: As discussed, it’s crucial for creating APIs and drug candidates, where the thiophene moiety is a recurring structural element.
  • Agrochemicals: Similar to pharmaceuticals, it can be used in the synthesis of compounds for agricultural applications.
  • Materials Science: Its derivatives can be explored for applications in electronic materials, polymers, and specialty coatings due to the unique electronic properties of the thiophene ring.

The Importance of Purity and Sourcing

When you need to purchase 3-Bromothiophene, especially for demanding applications, focusing on purity is paramount. A high purity level, such as 98%, ensures that your synthesis reactions proceed smoothly with minimal unwanted side products. This level of purity is typically achieved through meticulous manufacturing and purification processes by specialized chemical companies.

As a buyer, consider the benefits of sourcing from a reliable manufacturer and supplier. Companies that specialize in fine chemicals often have:

  • Consistent Quality: They maintain strict quality control measures to ensure that each batch of 3-Bromothiophene meets specification.
  • Bulk Supply Capability: They can handle orders of various sizes, from laboratory research quantities to commercial production volumes.
  • Competitive Pricing: Sourcing from established manufacturers, particularly those in regions like China, can lead to more cost-effective procurement. Obtaining a detailed quote for your required volume is the first step to securing this valuable intermediate.

In conclusion, 3-Bromothiophene is a foundational fine chemical intermediate whose versatility makes it indispensable in numerous synthetic endeavors. By prioritizing high purity and partnering with credible suppliers, researchers and manufacturers can effectively harness its potential to drive innovation across various scientific and industrial fields.