The pharmaceutical industry constantly seeks innovative molecules to address complex health challenges. Central to this endeavor is the availability of high-quality chemical intermediates that serve as foundational building blocks for novel drug candidates. 3-Chloro-4-fluorobenzotrifluoride (CAS 78068-85-6) has emerged as a key player in this arena, offering unique chemical properties that facilitate the synthesis of advanced pharmaceuticals. This article highlights its significance and guides professionals on sourcing this vital compound.

The Chemical Significance of 3-Chloro-4-fluorobenzotrifluoride

With the chemical formula C7H3ClF4 and identified by CAS number 78068-85-6, 3-Chloro-4-fluorobenzotrifluoride is a fluorinated aromatic intermediate. The presence of chlorine, fluorine, and a trifluoromethyl group on the benzene ring imparts distinct reactivity and stability, making it highly valuable in synthetic organic chemistry. Its typical presentation as a colorless transparent liquid, with a boiling point of approximately 137°C and a density around 1.45 g/cm³, are important characteristics for its application in synthesis. The high purity, typically above 98%, is critical for ensuring the success and efficiency of complex drug synthesis pathways, preventing unwanted byproducts and ensuring the integrity of the final API.

Applications in Pharmaceutical R&D

The primary application of 3-Chloro-4-fluorobenzotrifluoride lies in its role as an intermediate for synthesizing Active Pharmaceutical Ingredients (APIs). Its unique structure allows chemists to introduce fluorine atoms and trifluoromethyl groups into molecules, which can significantly influence properties such as metabolic stability, lipophilicity, and receptor binding affinity. This is crucial for developing drugs with enhanced therapeutic efficacy and improved pharmacokinetic profiles. For instance, it is used in the synthesis of compounds aimed at treating metabolic disorders, such as GPR40 agonists. Researchers looking to buy this intermediate are essentially investing in a tool that can accelerate drug discovery and development.

Finding a Reliable Manufacturer and Supplier

For pharmaceutical researchers and procurement specialists, securing a consistent supply of high-quality 3-Chloro-4-fluorobenzotrifluoride is vital. When considering where to purchase this compound, it is essential to partner with a reputable manufacturer that prioritizes quality control and offers competitive pricing. NINGBO INNO PHARMCHEM CO.,LTD. stands as a leading manufacturer and supplier in China, specializing in fine chemical intermediates. We are dedicated to providing 3-Chloro-4-fluorobenzotrifluoride with guaranteed purity (≥98.0%) and reliable delivery. Our commitment extends to offering responsive customer service and comprehensive product documentation, including Safety Data Sheets (SDS) and Certificates of Analysis (CoA).

The Benefits of Partnering with NINGBO INNO PHARMCHEM CO.,LTD.

By choosing NINGBO INNO PHARMCHEM CO.,LTD. as your supplier, you gain access to a dedicated partner focused on supporting your R&D efforts. We understand the critical timelines in pharmaceutical discovery and are equipped to meet varying order requirements, from small research quantities to larger-scale production needs. Our competitive pricing structures make high-purity intermediates accessible, enabling greater flexibility in budgeting for research projects. We invite you to contact us for a quote and to learn more about how our expertise and product offerings can benefit your pharmaceutical discovery process.

In conclusion, 3-Chloro-4-fluorobenzotrifluoride is an indispensable intermediate for modern pharmaceutical synthesis. By sourcing this compound from a trusted manufacturer like NINGBO INNO PHARMCHEM CO.,LTD., you can ensure the quality and reliability needed to drive your drug discovery programs forward.