3-Chloro-4-methylbenzoic Acid, identified by its CAS number 5162-82-3, is a significant organic compound widely utilized across various chemical sectors. This article delves into its essential properties, common synthesis routes, and its pivotal applications, providing valuable insights for industry professionals seeking to procure or utilize this chemical.

Chemical Identity and Physical Properties

3-Chloro-4-methylbenzoic Acid is a substituted benzoic acid derivative. Its typical appearance is a white to light yellow crystalline powder. Key physical characteristics reported include a melting point around 208 °C and a boiling point of 105-107 °C at reduced pressure (6.5 Torr). It exhibits solubility in solvents like DMSO (sparingly) and methanol (slightly). These properties are critical for formulators and chemists to consider during reaction planning and material handling.

Synthesis Pathways and Production

The synthesis of 3-Chloro-4-methylbenzoic Acid can be achieved through various established chemical routes. Common starting materials often involve substituted toluenes or benzoic acids, undergoing chlorination and oxidation steps. For instance, derivatives of p-toluic acid or related chlorinated aromatic compounds can be employed. Manufacturers often optimize these processes for yield, purity, and cost-effectiveness, ensuring a stable supply for the market. Understanding the production process can also shed light on potential impurity profiles, which is crucial for pharmaceutical applications.

Diverse Industrial Applications

The primary utility of 3-Chloro-4-methylbenzoic Acid lies in its role as a versatile intermediate. Its applications span several key industries:

  • Pharmaceutical Intermediates: It is a crucial building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). Its structure can be modified to create molecules with targeted pharmacological activities, aiding in the development of new drugs for various therapeutic areas.
  • Agrochemicals: In the agricultural sector, this compound is employed in the formulation of herbicides and pesticides. It contributes to the efficacy and performance of crop protection products, helping to enhance agricultural productivity.
  • Organic Synthesis and Research: As a reactive organic molecule, it is frequently used in academic and industrial research laboratories for the synthesis of novel compounds, complex organic structures, and for exploring new chemical reactions.
  • Specialty Chemicals: Its unique chemical structure also lends itself to the production of various specialty chemicals used in materials science and other industrial applications.

Procurement and Supply Chain Considerations

When seeking to purchase 3-Chloro-4-methylbenzoic Acid, it is important to partner with reputable manufacturers and suppliers who can guarantee high purity (often ≥97% or ≥98%) and consistent quality. Buyers should look for suppliers who provide comprehensive technical documentation, including Certificates of Analysis (CoA) and Safety Data Sheets (SDS). Manufacturers based in China are significant suppliers of this intermediate, offering competitive pricing and global shipping capabilities. Requesting a detailed quote based on the CAS number 5162-82-3 and the required quantity is the best approach for procurement.

Conclusion

3-Chloro-4-methylbenzoic Acid (CAS: 5162-82-3) is a cornerstone intermediate that fuels innovation across critical industries. Its specific chemical properties and broad application scope make it an essential compound for chemists and manufacturers alike. By prioritizing quality sourcing from trusted suppliers, businesses can ensure the successful development and production of their advanced chemical products.