In the dynamic field of pharmaceutical development, the selection of high-quality chemical intermediates is fundamental to creating safe and effective therapeutic agents. 3-Fluoro-4-nitrophenol (CAS 394-41-2) has emerged as a compound of significant interest, serving as a critical building block for a range of pharmaceutical applications. Understanding its chemical properties and its role as a versatile intermediate allows R&D scientists and procurement managers to make informed decisions when looking to buy pharmaceutical intermediates.

Chemical Profile of 3-Fluoro-4-nitrophenol

3-Fluoro-4-nitrophenol is an organic compound characterized by a substituted phenolic structure. Its molecular formula, C6H4FNO3, and molecular weight of approximately 157.10 g/mol, along with its CAS number 394-41-2, uniquely identify it. Typically supplied as a pale yellow to brown powder, its purity is often specified at 98% or higher, crucial for reactions where impurities can compromise the final product or lead to unwanted side reactions. This purity is meticulously managed by reputable chemical manufacturers.

Significance in Pharmaceutical Synthesis

The utility of 3-Fluoro-4-nitrophenol in pharmaceutical synthesis stems from its functional groups, which can be readily modified through various chemical transformations. It acts as a scaffold for building more complex molecules, including:

  • Active Pharmaceutical Ingredients (APIs): Researchers leverage this intermediate to construct novel drug candidates and to synthesize existing APIs where the fluorinated nitrobenzene moiety is a key structural feature.
  • Drug Discovery Programs: In early-stage drug discovery, its predictable reactivity allows for the rapid synthesis of diverse compound libraries for screening against biological targets.
  • Specialty Reagents: It can also be modified to create specialty reagents used in specific synthetic pathways within pharmaceutical research.

For companies that require a consistent and reliable supply of this essential compound, partnering with an experienced supplier in China offers significant advantages in terms of cost-effectiveness and availability. When searching to purchase pharmaceutical intermediates, it is vital to ensure the supplier provides detailed product specifications and a traceable supply chain.

Sourcing and Quality Assurance

When a pharmaceutical company seeks to buy 3-Fluoro-4-nitrophenol, paramount importance is placed on the quality and consistency of the material. Reputable suppliers provide comprehensive Certificates of Analysis (CoA) that verify purity, identify any impurities, and confirm adherence to specifications. Engaging with a well-established fine chemical supplier not only guarantees product quality but also ensures regulatory compliance and a stable supply for manufacturing processes. We encourage R&D professionals and procurement managers to request a quote from our experienced team, a leading manufacturer known for its commitment to quality in the pharmaceutical intermediates sector.