In the realm of fine chemicals, certain compounds stand out for their broad applicability and essential roles in various industries. 3-Hydroxypyridine, known by its CAS number 109-00-2, is one such compound. This aromatic heterocyclic molecule has garnered significant attention for its utility in pharmaceutical synthesis, agrochemical development, and analytical chemistry. Understanding its properties and sourcing effectively is crucial for businesses operating in these sectors.

Chemical Profile of 3-Hydroxypyridine

3-Hydroxypyridine, often referred to as 3-pyridinol, possesses a molecular formula of C5H5NO and a molecular weight of 95.1 g/mol. Its key physical characteristics include a melting point typically between 125-130°C and a crystalline powder appearance, often described as beige to brown. The compound exhibits moderate solubility in water (33g/L at 20°C) and good solubility in various organic solvents. The presence of both a pyridine nitrogen and a hydroxyl group confers bifunctional reactivity, enabling it to participate in a wide array of chemical reactions.

Key Applications Driving Demand

The versatility of 3-Hydroxypyridine underpins its importance across multiple industrial applications:

  • Pharmaceutical Industry: It serves as a crucial intermediate in the synthesis of numerous active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders and inflammatory conditions. Its structure provides a valuable scaffold for medicinal chemists developing novel therapeutics.
  • Agrochemical Sector: 3-Hydroxypyridine is utilized in the formulation of effective herbicides and fungicides, contributing to improved crop protection and yield enhancement. This role is vital for global food production.
  • Analytical Chemistry: Its ability to chelate metal ions makes it a useful reagent in analytical methods for trace metal analysis in environmental or biological samples.
  • Organic Synthesis: As a versatile building block, it is employed in a wide range of organic synthesis projects, from laboratory research to pilot-scale production of fine chemicals.

Global Sourcing and Procurement Considerations

For businesses seeking to purchase 3-Hydroxypyridine, sourcing from reliable global manufacturers is key to ensuring quality, availability, and competitive pricing. China remains a significant hub for fine chemical production, offering efficient manufacturing processes and cost advantages. When procuring CAS 109-00-2, buyers should prioritize:

  • Purity and Quality Assurance: Seek suppliers who provide high-purity material (e.g., ≥98%) with comprehensive Certificates of Analysis (CoA).
  • Manufacturer Reliability: Partner with established manufacturers known for consistent production quality and dependable supply chains.
  • Competitive Pricing: Obtain multiple quotes for bulk purchases to secure cost-effective solutions.
  • Technical Support: Engage with suppliers who offer robust technical documentation and support for their products.

Conclusion

3-Hydroxypyridine is a multifaceted chemical compound with indispensable applications in the pharmaceutical and agrochemical industries, among others. Its unique chemical properties make it a valuable intermediate for innovation. By focusing on sourcing from reputable manufacturers and paying close attention to quality and price, businesses can effectively leverage 3-Hydroxypyridine to achieve their research and production goals. If you are looking to buy this essential chemical, exploring reliable suppliers from China can offer a strategic advantage.