In the intricate world of organic synthesis, certain chemical intermediates stand out for their versatility and critical role in constructing complex molecules. 3-Iodobenzoic Acid (CAS: 618-51-9) is one such compound, widely recognized for its utility in various synthetic transformations, particularly within the pharmaceutical and fine chemical sectors. For chemists and manufacturers seeking to enhance their synthetic capabilities, understanding the properties and applications of this iodinated benzoic acid derivative is key.

Chemical Properties and Reactivity of 3-Iodobenzoic Acid

3-Iodobenzoic Acid, with its molecular formula C7H5IO2, presents a unique combination of a carboxylic acid group and an iodine substituent on an aromatic ring. The iodine atom, being a good leaving group, makes the meta-position of the benzene ring highly amenable to nucleophilic aromatic substitution and, more importantly, to a variety of transition-metal-catalyzed cross-coupling reactions. These reactions, including palladium-catalyzed couplings like the Suzuki, Stille, and Sonogashira reactions, are indispensable tools for forming new carbon-carbon bonds, which is fundamental to building the complex structures found in many APIs and specialty chemicals.

The carboxylic acid functionality also offers further avenues for chemical modification, such as esterification, amidation, or reduction, adding to the compound's versatility as a chemical building block. Its typical appearance as a white to off-white powder, with a melting point around 185-187 °C, also makes it relatively straightforward to handle in laboratory and industrial settings. When sourcing this material, quality is paramount; therefore, identifying a reliable manufacturer that can supply high-purity 3-Iodobenzoic Acid (e.g., 98% min) is crucial for predictable synthetic outcomes.

Applications Across Industries

The primary utility of 3-Iodobenzoic Acid lies in its role as a pharmaceutical intermediate. It serves as a key precursor in the synthesis of numerous APIs, where its specific structure and reactivity contribute to the creation of targeted therapeutic agents. Beyond pharmaceuticals, this compound is also valuable in the agrochemical industry for the synthesis of crop protection agents and in the development of advanced materials, including certain polymers and electronic chemicals, where precise molecular architecture is required.

For researchers and process developers, having access to dependable sources for such intermediates is vital. Whether you are looking to buy 3-Iodobenzoic Acid for early-stage R&D or for large-scale manufacturing, engaging with experienced chemical suppliers ensures you receive material that meets stringent quality standards. Understanding the pricing structures and the benefits of bulk purchase from a trusted 3-Iodobenzoic Acid manufacturer can optimize your procurement strategy.

Sourcing and Partnership

When you decide to purchase 3-Iodobenzoic Acid, partnering with a reputable supplier, especially one with a strong presence in China, can provide significant advantages. These suppliers often offer competitive pricing for high-purity chemicals, along with flexible packaging and efficient logistics. For procurement specialists, requesting a quote and obtaining samples are essential steps to validate quality and suitability. Building a relationship with a consistent supplier of CAS 618-51-9 can secure your supply chain and contribute to the overall success of your chemical synthesis projects.

In conclusion, 3-Iodobenzoic Acid is a cornerstone intermediate in modern organic synthesis, enabling the creation of sophisticated molecules across various industries. Its reactivity and versatility make it a valuable asset for any chemistry-focused enterprise. To secure your supply of this essential compound, reach out to us for competitive pricing and high-quality material.